Also known as: Lyme Test, Lyme Disease Test, Lyme Titer, Lyme Antibody Test with Reflex
Hospital Lab
$200
cash pay
Other Labs
$65
+ lab fees
TestWell
$40.99
+ $6 lab fee
Lyme disease testing follows the CDC-recommended two-tier approach. The first tier is an ELISA or immunoassay that screens for Lyme antibodies. If the screen is positive or equivocal, a confirmatory Western blot is performed. This reflex approach reduces false positives while maintaining high sensitivity. Testing is most accurate 4–6 weeks after a suspected tick bite.
Two-tier Lyme serology: ELISA screen followed automatically by a Western blot confirmatory test if positive — the CDC-recommended diagnostic algorithm.
Anyone with known tick exposure, characteristic erythema migrans (bullseye) rash, or unexplained fevers/joint pains/neuropathy living in or recently visited a Lyme-endemic region (Northeast, mid-Atlantic, upper Midwest, parts of CA/OR).
Sample Type
Blood draw
Fasting
Not required
Results In
3–7 business days
Performed At
Quest
3 biomarkers tested
Your Lyme Disease Serology with Reflex results will include values for each of the 3 biomarkers tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 3–7 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you.
Your Lyme Disease Serology with Reflex results will include values for each of the 3 biomarkers tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 3–7 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you.
No fasting required. Testing is most accurate 4–6 weeks after a suspected tick bite.
No fasting required. Testing is most accurate 4–6 weeks after a suspected tick bite.
TestWell Price
$40.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Frequently ordered together
Customers who ordered Lyme Disease Serology with Reflex also added these for a more complete health picture.
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Lyme Disease Serology with Reflex
$40.99