What is the Quest Diagnostics test code for a Lyme Disease test?

Quest Diagnostics test code 6646. On a Quest Diagnostics requisition the test is printed as "Lyme Disease Ab with Reflex to Blot (IgG, IgM)", billing code CPT 86618. If you are holding a doctor's order, that is the line to look for; a TestWell requisition carries the same code.

Can I walk into Quest Diagnostics for a Lyme Disease test without a doctor?

Yes, with a requisition. Quest Diagnostics patient service centers draw what a requisition orders; they do not write orders. You can get one from your doctor, buy the test on Quest Health ($100.00), or order through TestWell ($64.99 + $6 fee), where a licensed physician in our network authorizes the order and the Quest Diagnostics requisition arrives by email, usually within minutes. New York and New Jersey do not allow self-ordered draws at Quest or Labcorp; TestWell orders from those states route to BioReference instead.

Do I need an appointment at Quest Diagnostics?

Most Quest Diagnostics patient service centers take walk-ins, and an appointment on Quest Diagnostics's site shortens the wait. Bring a photo ID and the emailed requisition (on your phone is fine). No fasting is required for this test. No fasting required. Testing is most accurate 4–6 weeks after a suspected tick bite.

How long do Quest Diagnostics Lyme Disease results take?

Results post to your TestWell portal in 3–7 business days after the draw, with reference ranges and the option to share them with your clinician. Quest Diagnostics runs the sample in its own CLIA-certified laboratory whichever way it was ordered, so the result and the turnaround are the same as a doctor-ordered Lyme Disease test.

Is a Lyme Disease test cheaper at Quest Diagnostics or Labcorp?

Through TestWell this test is drawn at Quest Diagnostics only ($64.99 + $6 fee); it is not offered at Labcorp. Quest Health lists it at $100.00.

Lyme Disease Serology with Reflex at Quest Diagnostics: test code, price, and how to order

Quest Health, Quest Diagnostics's own consumer site, lists the Lyme Disease test at $100.00 (list price checked Oct 10, 2026; both include reflex confirmation of positive screens). Through TestWell the same Quest Diagnostics draw is $64.99 plus one $6 lab processing fee — $70.99 all-in, $29.01 less for a single test, and the fee is per order, so adding tests widens the gap. Either way you walk into a Quest Diagnostics patient service center with a requisition — through TestWell a licensed physician authorizes the order, no doctor's visit needed.

$70.99 all-in for one test · choose Quest Diagnostics at checkout · results in 3–7 business days · no fasting

Lyme Disease at Quest Diagnostics at a glance

Quest Diagnostics test code	6646
On the requisition	“Lyme Disease Ab with Reflex to Blot (IgG, IgM)” · CPT 86618
Quest Health price (Quest Diagnostics's own site)	$100.00 · list price checked Oct 10, 2026 · Both include reflex confirmation of positive screens
Through TestWell, drawn at Quest Diagnostics	$64.99 + $6 lab processing fee (once per order) = $70.99 for one test
Sample · fasting · results	Blood draw · no fasting · 3–7 business days

$29.01 less than Quest Health for a single test; the fee is per order, so the difference grows with each test added. Lab-direct prices are read from the linked public page and re-checked regularly; the lab's site may add fees at checkout or change prices without notice.

Three ways to get a Lyme Disease test at Quest Diagnostics

With a doctor's order. Your clinician sends a requisition to Quest Diagnostics; the lab bills your insurance and your share depends on your plan and deductible. Ask for the Quest Diagnostics test code 6646 if you want the same test.
On Quest Health. Quest Diagnostics's consumer site sells the Lyme Disease test at $100.00 (list price, checked Oct 10, 2026); a physician network authorizes it and you draw at a Quest Diagnostics center. Check their checkout for any service fee.
Through TestWell. $64.99 plus one $6 fee per order. A licensed physician in our network authorizes the order, the Quest Diagnostics requisition arrives by email (usually within minutes), you walk into any Quest Diagnostics patient service center, and results post to your portal in 3–7 business days. Add tests to the same draw without another fee.

How to walk into Quest Diagnostics with a TestWell order

Add the Lyme Disease test to your cart, choose Quest Diagnostics at checkout, and pay — a physician authorizes the order, usually within minutes.
Open the emailed requisition on your phone (or print it) and bring a photo ID.
Walk into any Quest Diagnostics patient service center; most take walk-ins, and an appointment on Quest Diagnostics's site shortens the wait.
Results post to your TestWell portal in 3–7 business days, with reference ranges and a share link for your clinician.

In New York or New Jersey? Neither Quest nor Labcorp takes self-ordered draws there; TestWell routes those orders to BioReference automatically.

Where to get a Lyme Disease test at Quest Diagnostics

Quest Diagnostics runs 418 patient service centers across the 45 metros TestWell tracks (snapshot Oct 10, 2026); the TestWell requisition is accepted at all of them. Metros with the most Quest Diagnostics sites:

All states and cities · Search by ZIP code

What the Quest Diagnostics Lyme Disease result covers

3 markers: Lyme IgG/IgM Antibody Screen, Western Blot IgG (if reactive), Western Blot IgM (if reactive). Two-tier testing for Lyme disease — screens with ELISA and confirms with Western blot if positive. Full test details, reference ranges and reviews.

Frequently asked questions

How much is a Lyme Disease test at Quest Diagnostics?: Quest Health, Quest Diagnostics's own consumer site, lists the Lyme Disease test at $100.00 (list price checked Oct 10, 2026; both include reflex confirmation of positive screens). Through TestWell the same Quest Diagnostics draw is $64.99 plus one $6 lab processing fee — $70.99 all-in, $29.01 less for a single test, and the fee is per order, so adding tests widens the gap. Either way you walk into a Quest Diagnostics patient service center with a requisition — through TestWell a licensed physician authorizes the order, no doctor's visit needed.
What is the Quest Diagnostics test code for a Lyme Disease test?: Quest Diagnostics test code 6646. On a Quest Diagnostics requisition the test is printed as "Lyme Disease Ab with Reflex to Blot (IgG, IgM)", billing code CPT 86618. If you are holding a doctor's order, that is the line to look for; a TestWell requisition carries the same code.
Can I walk into Quest Diagnostics for a Lyme Disease test without a doctor?: Yes, with a requisition. Quest Diagnostics patient service centers draw what a requisition orders; they do not write orders. You can get one from your doctor, buy the test on Quest Health ($100.00), or order through TestWell ($64.99 + $6 fee), where a licensed physician in our network authorizes the order and the Quest Diagnostics requisition arrives by email, usually within minutes. New York and New Jersey do not allow self-ordered draws at Quest or Labcorp; TestWell orders from those states route to BioReference instead.
Do I need an appointment at Quest Diagnostics?: Most Quest Diagnostics patient service centers take walk-ins, and an appointment on Quest Diagnostics's site shortens the wait. Bring a photo ID and the emailed requisition (on your phone is fine). No fasting is required for this test. No fasting required. Testing is most accurate 4–6 weeks after a suspected tick bite.
How long do Quest Diagnostics Lyme Disease results take?: Results post to your TestWell portal in 3–7 business days after the draw, with reference ranges and the option to share them with your clinician. Quest Diagnostics runs the sample in its own CLIA-certified laboratory whichever way it was ordered, so the result and the turnaround are the same as a doctor-ordered Lyme Disease test.
Is a Lyme Disease test cheaper at Quest Diagnostics or Labcorp?: Through TestWell this test is drawn at Quest Diagnostics only ($64.99 + $6 fee); it is not offered at Labcorp. Quest Health lists it at $100.00.

Order the Lyme Disease test — $64.99 at Quest Diagnostics