The short answer
HIV 1/2 Antigen & Antibodies (4th Gen) measures HIV-1/2 Antibodies and HIV p24 Antigen from a standard blood draw. At TestWell it costs $39.99 plus a $6 lab fee, needs no fasting, and results post in 1–4 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Labcorp.
Hospital Lab
$150
cash pay
Other Labs
$55
+ lab fees
TestWell
$39.99
+ $6 lab fee
The fourth-generation HIV test detects both HIV-1/HIV-2 antibodies and the p24 antigen, allowing for earlier detection than antibody-only tests. It can detect HIV as early as 2–4 weeks after exposure (compared to 3–12 weeks for older tests). This is the CDC-recommended screening method for all adults aged 15–65. The test includes reflexes to confirmatory testing if the screen is positive.
4th-generation HIV test detects both HIV antibodies and the p24 antigen — catches infection as early as 2-4 weeks post-exposure. Recommended annual screening per CDC for at-risk adults; one-time screening for all adults 18-65.
Any sexually active adult per CDC routine-screening guidance, anyone with new partners, post-exposure screening (3 weeks after exposure for 4th-gen testing), routine MSM testing every 3-6 months, anyone with symptoms of acute HIV (flu-like illness 2-4 weeks after exposure).
Sample Type
Blood draw
Fasting
Not required
Results In
1–4 business days
Performed At
Labcorp
2 biomarkers tested
Your HIV 1/2 Antigen & Antibodies (4th Gen) results will include values for each of the 2 biomarkers tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 1–4 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you.
No fasting required. No special preparation needed. Window period: 2–4 weeks after exposure.
A HIV 1/2 Antigen & Antibodies (4th Gen) test costs $39.99 at TestWell — $45.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the closest equivalent lists at $85.00 at Quest Health and $99.00 at Labcorp OnDemand (list prices checked Sep 12, 2026; see the notes on how the products differ). Hospital outpatient labs typically bill around $150.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest or Labcorp) | $39.99 | $45.99 | Includes the one $6 lab processing fee, charged once per order |
| Quest Health (Quest Diagnostics' own site) | $85.00 | $85.00 | Both are 4th-generation antigen/antibody screens with confirmation · list price checked Sep 12, 2026 |
| Labcorp OnDemand (Labcorp's own site) | $99.00 | $99.00 | list price checked Sep 12, 2026 |
| Hospital outpatient lab, self-pay (typical) | $150.00 | $150.00 | Reference figure; hospital charges vary widely by facility and are often higher |
46% less than the lower lab-direct list price, for the same draw at the same lab. Lab test codes: Quest test code 91431 · Labcorp test no. 083935 · BioReference code B688-3. Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
TestWell Price
$39.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Better value: the STI Basic Panel
Save $7.99This test is part of the STI Basic Panel — 2 tests · 4 biomarkers for $84.99, $7.99 less than à la carte.
$84.99$92.98
2 tests · 4 biomarkers
Frequently ordered together
Customers who ordered HIV 1/2 Antigen & Antibodies (4th Gen) also added these for a more complete health picture.
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HIV 1/2 Antigen & Antibodies (4th Gen)
$39.99