Quarterly monitoring for women on hormone replacement therapy
The short answer
Female HRT Quarterly Monitoring Panel bundles 12 tests — CBC (Complete Blood Count), Comprehensive Metabolic Panel and Estradiol (E2) plus 9 more — for $179.99 plus one $6 lab processing fee (about $15.00 per test). Fast 8–12 hours before the draw; results post in 2-4 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest.
Other Labs
Starting at $289
+ lab fees
TestWell
$179.99
+ $6 lab processing fee
This quarterly monitoring panel tracks the key markers your HRT provider needs to assess therapeutic response and safety. It includes reproductive hormones (estradiol, progesterone, testosterone total and free, FSH, LH, SHBG), thyroid function (TSH), metabolic markers (fasting glucose via CMP, lipid panel), blood health (CBC), and inflammation (hs-CRP). Regular monitoring every 3 months allows your provider to fine-tune dosing and catch any metabolic changes early. Fast for 10-12 hours before the blood draw and note the day of your cycle when labs are drawn.
Female HRT monitoring: Estradiol, Progesterone, Testosterone, SHBG, TSH, Lipid Panel, hs-CRP, CMP. The standard quarterly workup recommended during HRT titration and ongoing therapy.
Women currently on hormone replacement therapy. Recommended every 3-6 months during dose titration and the first year, then every 6-12 months once stable.
Sample Type
Blood draw
Fasting
Required
Results In
2-4 business days
Biomarkers
36 across 12 tests
12 individual tests · 36 biomarkers measured — each test linked so you can learn more.
Fasting for 10-12 hours is required for accurate glucose and lipid results. Water is okay. Lab draw is recommended on Day 2-3 of your menstrual cycle for the most accurate hormone levels. Morning draw preferred.
What can throw off this result
Physician-reviewed “Before your test” pages — what each factor does, for how long, and what to do about it.
A Female HRT Quarterly Monitoring Panel costs $179.99 at TestWell — $185.99 all-in, since the $6 lab processing fee is charged once per order and there is no draw or physician fee. With insurance you pay your plan's negotiated rate against your deductible; TestWell's price is fixed before the draw and HSA/FSA-eligible.
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest or Labcorp) | $179.99 | $185.99 | Includes the one $6 lab processing fee, charged once per order |
Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Estradiol, Progesterone, Testosterone, SHBG, TSH, Lipid Panel, hs-CRP, CMP. About 20 biomarkers for dose effectiveness and safety monitoring.
Depends on symptoms and HRT type. General targets: oral estradiol 50-100 pg/mL; transdermal patch 40-80 pg/mL; cream/gel 30-60 pg/mL. Many women feel best at the higher end. Always interpret in context of symptoms — labs alone don't tell the whole story.
For patches: ~24-48 hours after application (steady state). For oral: 2-4 hours after dose (peak) or trough at 24 hours. For creams/gels: 2-4 hours after morning application. For pellets: at month 3 post-insertion (mid-cycle steady state). Consistency matters more than the exact time — always draw at the same point in your dosing cycle.
On TestWell, the Female HRT Quarterly Panel is $179.99. Ordering the same tests separately would be about $230. Quest Health lists comparable bundles at $289, walk-in hospital labs typically bill $500-800 without insurance.
HRT Starting Panel at $250 is more comprehensive — adds FSH, LH, CBC. HRT Quarterly focuses on dose effectiveness (Estradiol, Progesterone, Testosterone) plus safety monitoring (Lipid, hs-CRP, CMP). Quarterly is the right ongoing-monitoring panel; Starting is the right pre-therapy panel.
Every 6-8 weeks during initial titration. Every 3-6 months in the first year. Annually once stable on goal dose with stable symptoms. More frequently if symptoms change, dose is adjusted, or you switch HRT formulations.
Female HRT Quarterly Monitoring Panel results are typically ready in 2-4 business days after your draw at Quest or Labcorp. TestWell emails you the moment they post, and your results dashboard shows each marker against its reference range with a plain-English explanation.
Yes. Fasting for 10-12 hours is required for accurate glucose and lipid results. Water is okay. Lab draw is recommended on Day 2-3 of your menstrual cycle for the most accurate hormone levels. Morning draw preferred. The fasting before blood work guide covers how long to fast, what you can drink, and which results eating changes.
Keto and high-protein diets and smoking and nicotine can change a Female HRT Quarterly Monitoring Panel result without anything being wrong. Keto and high-protein diets can raise LDL Cholesterol and HDL Cholesterol and 2 more markers on this test and can lower Triglycerides, Sodium and Glucose — recheck with ApoB; discuss cardiovascular risk rather than dismissing the rise as 'diet noise'. Smoking and nicotine can raise RBC and WBC and 3 more markers on this test and can lower HDL Cholesterol — tell the clinician; a high hematocrit in a smoker is usually smoking, not polycythemia. Each is explained on our physician-reviewed "Before your test" pages; when one applies, remove it and retest.
Order the Female HRT Quarterly Monitoring Panel online from TestWell for $179.99 (plus a $6 per-order lab processing fee) — no doctor's visit, referral or insurance needed. A licensed physician authorizes the order, then you walk into any Quest or Labcorp patient service center near you for the draw (the lab locator on our site lists the closest ones by ZIP code), and results arrive in 2-4 business days.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
Starting at $289 at other labs
TestWell Price
$179.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Individual tests that complement this panel
Female HRT Quarterly Monitoring Panel
$179.99