The short answer
The primary form of estrogen — essential for reproductive health, bone density, and menopause assessment, measured from a standard blood draw. At TestWell it costs $35.99 plus a $6 lab fee, needs no fasting, and results post in 1–3 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp.
Hospital Lab
$200
cash pay
Other Labs
$79
+ lab fees
TestWell
$35.99
+ $6 lab fee
Estradiol (E2) is the most potent and prevalent form of estrogen in premenopausal women. It plays a critical role in menstrual cycle regulation, bone health, cholesterol metabolism, and reproductive function. Testing estradiol helps evaluate fertility, menstrual irregularities, menopause status, and hormone therapy. In men, elevated estradiol can cause gynecomastia and other symptoms.
Primary estrogen in reproductive-age women. Used to evaluate ovarian function, menstrual irregularities, fertility, and menopausal status. Also monitored in men on TRT to track aromatization.
Women with irregular periods, infertility workup, suspected perimenopause/menopause, or monitoring HRT. Men on TRT to monitor aromatization to estrogen.
Sample Type
Blood draw
Fasting
Not required
Results In
1–3 business days
Performed At
Quest or Labcorp
Your Estradiol (E2) results will include values for each of the 1 biomarker tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 1–3 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you.
No fasting required. Women: best tested on day 3 of the menstrual cycle for fertility evaluation.
A Estradiol (E2) test costs $35.99 at TestWell — $41.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the same test lists at $79.00 at Labcorp OnDemand (list prices checked Sep 12, 2026). Hospital outpatient labs typically bill around $200.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. Full cost breakdown →
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest or Labcorp) | $35.99 | $41.99 | Includes the one $6 lab processing fee, charged once per order |
| Labcorp OnDemand (Labcorp's own site) | $79.00 | $79.00 | list price checked Sep 12, 2026 |
| Hospital outpatient lab, self-pay (typical) | $200.00 | $200.00 | Reference figure; hospital charges vary widely by facility and are often higher |
47% less than the lower lab-direct list price, for the same draw at the same lab. Lab test codes: Quest test code 4021 · Labcorp test no. 004515 · BioReference code 0516-5. Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
Related guide
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TestWell Price
$35.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Better value: the Women's Fertility Essentials
Save $89.96This test is part of the Women's Fertility Essentials — 5 tests · 5 biomarkers for $119.99, $89.96 less than à la carte.
$119.99$209.95
5 tests · 5 biomarkers
Frequently ordered together
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Estradiol (E2)
$35.99