The short answer
The primary form of estrogen — essential for reproductive health, bone density, and menopause assessment, measured from a standard blood draw. At TestWell it costs $35.99 plus a $6 lab processing fee, needs no fasting, and results post in 1–3 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp.
Hospital Lab
$200
cash pay
Other Labs
$79
+ lab fees
TestWell
$35.99
+ $6 lab processing fee
Estradiol (E2) is the most potent and prevalent form of estrogen in premenopausal women. It plays a critical role in menstrual cycle regulation, bone health, cholesterol metabolism, and reproductive function. Testing estradiol helps evaluate fertility, menstrual irregularities, menopause status, and hormone therapy. In men, elevated estradiol can cause gynecomastia and other symptoms.
Primary estrogen in reproductive-age women. Used to evaluate ovarian function, menstrual irregularities, fertility, and menopausal status. Also monitored in men on TRT to track aromatization.
Women with irregular periods, infertility workup, suspected perimenopause/menopause, or monitoring HRT. Men on TRT to monitor aromatization to estrogen.
Sample Type
Blood draw
Fasting
Not required
Results In
1–3 business days
Performed At
Quest or Labcorp
Your Estradiol (E2) results will include values for each of the 1 biomarker tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 1–3 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you. Already have results? Analyze them with your AI assistant against our physician-reviewed ranges.
No fasting required. Women: best tested on day 3 of the menstrual cycle for fertility evaluation.
What can throw off this result
Physician-reviewed “Before your test” pages — what each factor does, for how long, and what to do about it.
An Estradiol (E2) test costs $35.99 at TestWell — $41.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the same test lists at $79.00 at Labcorp OnDemand (list prices checked Sep 12, 2026). Hospital outpatient labs typically bill around $200.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. Full cost breakdown →
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest) | $35.99 | $41.99 | Includes the one $6 lab processing fee, charged once per order |
| TestWell (drawn at Labcorp) | $56.99 | $62.99 | Labcorp's own cost for this test is higher; same order, same portal, same physician review |
| TestWell (drawn at BioReference — New York & New Jersey) | $42.99 | $48.99 | New York and New Jersey orders route to BioReference; Quest Health and Labcorp OnDemand don't take self-ordered draws in those states |
| Labcorp OnDemand (Labcorp's own site) | $79.00 | $79.00 | list price checked Sep 12, 2026 |
| Hospital outpatient lab, self-pay (typical) | $200.00 | $200.00 | Reference figure; hospital charges vary widely by facility and are often higher |
47% less than the lower lab-direct list price, for the same draw at the same lab. Lab test codes: Quest test code 4021 · Labcorp test no. 004515 · BioReference code 0516-5. Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Day 3 of your cycle (counting day 1 as the first full day of bleeding) is the standard for ovarian-reserve evaluation — pair with FSH for a complete reserve picture. Mid-cycle (day 13-15) for ovulation tracking. Random for menopause assessment.
Reproductive-age women: 30-400 pg/mL depending on cycle phase (lowest in early follicular, peaks 200-400 at mid-cycle). Postmenopausal: under 30 pg/mL. Men: 10-40 pg/mL. On TRT, target 20-30 pg/mL.
Testosterone aromatizes (converts) to estradiol. Elevated estradiol on TRT can cause water retention, gynecomastia, mood swings, and breast tenderness. Monitor every 3 months while titrating TRT dose; add an aromatase inhibitor only if symptomatic and labs confirm elevation.
On TestWell, Estradiol is $35.99. Quest Direct lists the same test at $79, walk-in hospital labs typically bill $150-200 without insurance. Same CLIA-certified labs, same biomarker — TestWell just removes the markup.
The CPT code for estradiol (E2) is 82670. Most fertility/hormone workups bill 82670 alongside 83001 (FSH) and 83002 (LH).
No fasting required. But timing within the menstrual cycle matters more than fasting state — check your last menstrual period date before drawing.
Yes. For fertility workup, pair with FSH, LH, AMH, progesterone, prolactin. The Women's Hormone Panel bundles the core fertility hormones at a discount.
Ordered directly, an Estradiol (E2) test lists at $79.00 at Labcorp OnDemand (prices checked September 2026). TestWell orders the same test at the same Quest or Labcorp patient service centers for $35.99 — $41.99 all-in with the $6 per-order lab processing fee — paid out of pocket at checkout with no insurance, doctor's visit or draw fee; HSA and FSA cards are accepted.
Estradiol (E2) test results are typically ready in 1–3 business days after your draw at Quest or Labcorp. TestWell emails you the moment they post, and your results dashboard shows each marker against its reference range with a plain-English explanation.
Biotin supplements, cycle day, oral contraceptives and estrogen and peptides and GLP-1s can change an Estradiol (E2) test result without anything being wrong. Biotin supplements can shift Estradiol — stop biotin ≥72 hours; tell the lab if you can't. Cycle day can shift Estradiol — draw on cycle days 2–5 unless told otherwise. Oral contraceptives and estrogen can lower Estradiol — Cycle-day hormone testing is not meaningful on the pill or with a hormonal IUD/implant. Peptides and GLP-1s can shift Estradiol — monitor as for TRT: total/free testosterone, estradiol, CBC (hematocrit), PSA if over 40. Each factor is covered on our physician-reviewed "Before your test" pages; when one applies, the fix is usually to remove it and retest.
Order the Estradiol (E2) test online from TestWell for $35.99 (plus a $6 per-order lab processing fee) — no doctor's visit, referral or insurance needed. A licensed physician authorizes the order, then you walk into any Quest or Labcorp patient service center near you for the draw (the lab locator on our site lists the closest ones by ZIP code), and results arrive in 1–3 business days.
The Estradiol (E2) test is Quest Diagnostics test code 4021, Labcorp test number 004515, BioReference code 0516-5 (CPT 82670). TestWell orders it under those codes for $35.99 at Quest, Labcorp or BioReference — no doctor's visit or insurance required, results in 1–3 business days. Codes verified against the labs' catalogs in 2026.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
Related guide
Estradiol vs Estrogen Test: What Each Measures, Why Estradiol Is Usually the Right Order, and When Total Estrogens Makes Sense
Related guide
Blood Tests for Women's Health
TestWell Price
$35.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Better value: the Women's Fertility Essentials
Save $89.96This test is part of the Women's Fertility Essentials — 5 tests · 5 biomarkers for $119.99, $89.96 less than à la carte.
$119.99$209.95
5 tests · 5 biomarkers
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