ANA with reflex, rheumatoid factor and both inflammation markers — the first-line autoimmune work-up
The short answer
Autoimmune Screening Panel bundles 4 tests — Autoimmune Antibody Screen (ANA), Heart & Body Inflammation Test (hs-CRP) and Body Inflammation Test (ESR) plus 1 more — for $86.99 all-in (about $21.75 per test). No fasting is needed; results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp.
TestWell Price
$86.99
+ $6 lab processing fee
When symptoms suggest an autoimmune condition — joint pain and swelling, a photosensitive rash, unexplained fevers or fatigue, dry eyes and mouth, Raynaud's colour changes — the first blood tests answer two questions: is there systemic inflammation, and are there autoantibodies? This panel measures ESR and high-sensitivity CRP for inflammation, rheumatoid factor for rheumatoid arthritis, and an ANA screen that automatically reflexes to titer, pattern and the specific-antibody panel (anti-dsDNA, Smith, SSA/SSB, RNP, Scl-70, centromere, Jo-1) when positive — so a positive screen leaves with the antibodies that point toward lupus, Sjögren's or scleroderma instead of a second visit. Read the results together: a positive ANA alone is common in healthy people, while positive specific antibodies with raised inflammation markers and symptoms warrant a rheumatology referral. No fasting is needed.
Adults with persistent joint pain or swelling, unexplained rashes or fevers, dry eyes and mouth, Raynaud's, or a family history of lupus, rheumatoid arthritis or Sjögren's who want the first-line work-up before a specialist visit.
Sample Type
Blood draw
Fasting
Not required
Results In
3–5 business days
Biomarkers
6 across 4 tests
4 individual tests · 6 biomarkers measured — each test linked so you can learn more.
No fasting required. Avoid vigorous exercise for 24 hours before the draw (it can raise CRP). Tell your clinician about medications — several can cause a positive ANA.
A Autoimmune Screening Panel costs $86.99 at TestWell — $92.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest or Labcorp) | $86.99 | $92.99 | Includes the one $6 lab processing fee, charged once per order |
Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
TestWell Price
$86.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Individual tests that complement this panel
Autoimmune Screening Panel
$86.99