On your lab requisition: Quest “ANA Screen, IFA, Reflex Titer/Pattern, and Reflex to Multiplex 11 Ab Cascade” (test code 16814)Labcorp “Antinuclear Ab by Multiplex” (test no. 164855)BioReference “Antinuclear Ab. (ANA) W/Reflex” (test code 0038-0)
The short answer
Autoimmune Antibody Screen (ANA) measures ANA Screen, Titer (if positive) and Pattern (if positive) from a standard blood draw. At TestWell it costs $32.99 plus a $6 lab processing fee, needs no fasting, and results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp.
Hospital Lab
$180
cash pay
Other Labs
$60
+ lab fees
TestWell
$32.99
+ $6 lab processing fee
The Antinuclear Antibody (ANA) Screen uses immunofluorescence to detect antibodies that attack your own cell nuclei. A positive ANA can indicate autoimmune conditions including lupus (SLE), Sjögren's syndrome, scleroderma, rheumatoid arthritis, and mixed connective tissue disease. If positive, the reflex titer and pattern help narrow down the specific condition.
Antinuclear Antibody screen — the gateway test for systemic autoimmune disease. Positive in 95%+ of lupus, 60-80% of Sjögren's, and most autoimmune connective-tissue disorders.
Anyone with unexplained joint pain, rashes, fatigue, dry eyes/mouth, hair loss, or family history of autoimmune disease. The single best screening test before pursuing specific autoimmune workups.
Sample Type
Blood draw
Fasting
Not required
Results In
3–5 business days
Performed At
Quest or Labcorp
3 biomarkers tested
Your Autoimmune Antibody Screen (ANA) results will include values for each of the 3 biomarkers tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 3–5 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you. Already have results? Analyze them with your AI assistant against our physician-reviewed ranges.
No fasting required. No special preparation needed.
An Autoimmune Antibody Screen (ANA) costs $32.99 at TestWell — $38.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the closest equivalent lists at $112.00 at Quest Health (list prices checked Sep 12, 2026; see the notes on how the products differ). Hospital outpatient labs typically bill around $180.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. Full cost breakdown →
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest or Labcorp) | $32.99 | $38.99 | Includes the one $6 lab processing fee, charged once per order |
| TestWell (drawn at BioReference — New York & New Jersey) | $23.99 | $29.99 | New York and New Jersey orders route to BioReference; Quest Health and Labcorp OnDemand don't take self-ordered draws in those states |
| Quest Health (Quest Diagnostics' own site) | $112.00 | $112.00 | Both reflex to an antibody panel on a positive ANA · list price checked Sep 12, 2026 |
| Hospital outpatient lab, self-pay (typical) | $180.00 | $180.00 | Reference figure; hospital charges vary widely by facility and are often higher |
65% less than the lower lab-direct list price, for the same draw at the same lab. Lab test codes: Quest test code 16814 · Labcorp test no. 164855 · BioReference code 0038-0. Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
A positive ANA alone doesn't diagnose any specific condition. About 5-15% of healthy people have a low-titer positive ANA. Higher titers (1:320+) and specific patterns (homogeneous, speckled, nucleolar) point toward specific diseases — but a clinician needs to interpret in context with symptoms and follow-up specific antibody tests.
TestWell charges $32.99 — vs $49 at Quest Direct and $80-$200 at hospital labs.
ANA Screen reports positive/negative + titer + pattern. ANA with Reflex automatically runs specific antibody tests (anti-dsDNA, anti-Smith, anti-RNP, anti-SSA/SSB) if the screen is positive — saves a follow-up draw. We default to ANA with reflex for symptomatic patients.
Once positive, titer can change with disease activity. Retest every 3-6 months if monitoring an established autoimmune diagnosis; annually if positive but asymptomatic.
Ordered directly, the closest equivalent lists at $112.00 at Quest Health (Quest Diagnostics' own site) (prices checked September 2026). TestWell orders the same test at the same Quest or Labcorp patient service centers for $32.99 — $38.99 all-in with the $6 per-order lab processing fee — paid out of pocket at checkout with no insurance, doctor's visit or draw fee; HSA and FSA cards are accepted.
Autoimmune Antibody Screen (ANA) results are typically ready in 3–5 business days after your draw at Quest or Labcorp. TestWell emails you the moment they post, and your results dashboard shows each marker against its reference range with a plain-English explanation.
No, fasting is not required for an Autoimmune Antibody Screen (ANA) — you can eat normally and book any time of day.
Order the Autoimmune Antibody Screen (ANA) online from TestWell for $32.99 (plus a $6 per-order lab processing fee) — no doctor's visit, referral or insurance needed. A licensed physician authorizes the order, then you walk into any Quest or Labcorp patient service center near you for the draw (the lab locator on our site lists the closest ones by ZIP code), and results arrive in 3–5 business days.
The CPT code for an Autoimmune Antibody Screen (ANA) is 86038. You can order it from TestWell for $32.99 — no doctor's visit or insurance required, with results in 3–5 business days.
The Autoimmune Antibody Screen (ANA) is Quest Diagnostics test code 16814 ("ANA Screen, IFA, Reflex Titer/Pattern, and Reflex to Multiplex 11 Ab Cascade"), Labcorp test number 164855 ("Antinuclear Ab by Multiplex"), BioReference code 0038-0 ("Antinuclear Ab. (ANA) W/Reflex") (CPT 86038). TestWell orders it under those codes for $32.99 at Quest, Labcorp or BioReference — no doctor's visit or insurance required, results in 3–5 business days. Codes verified against the labs' catalogs in 2026.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
Related guide
ANA Test Results Explained: Titers, Patterns, and What a Positive ANA Means
TestWell Price
$32.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Better value: the Autoimmune Screening Panel
Save $21.97This test is part of the Autoimmune Screening Panel — 4 tests · 6 biomarkers for $86.99, $21.97 less than à la carte.
$86.99$108.96
4 tests · 6 biomarkers
Frequently ordered together
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Autoimmune Antibody Screen (ANA)
$32.99