TPO Antibodies levels: what's normal, high and low
Antibodies against thyroid peroxidase. The most common marker of autoimmune thyroid disease.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
The short answer
TPO Antibodies is measured with a standard blood draw; no fasting is needed. A typical reference range is 0.000 – 35.0 IU/mL. At TestWell it's $51.99 all-in as Thyroid Antibodies, results in 3–5 business days, drawn at Quest or Labcorp. An out-of-range result is a prompt to look closer, not a diagnosis.
- Units
- IU/mL
- Sample
- Blood draw
- Fasting
- Not required
- Results
- 3–5 business days
- Price
- $51.99
- Labs
- Quest or Labcorp
TPO Antibodies Reference Range
These are the typical adult reference ranges used by major US labs. Your report will include the specific range used by the lab that processed your sample.
| Population | Range |
|---|---|
| age 18+ | 0.000 – 35.0 IU/mL |
Reference ranges are educational. Always interpret your result with the specific range printed on your lab report and discuss anything outside the range with a clinician.
What your TPO Antibodies result may mean
Often reflects Hashimoto's (most common) or Graves' disease. Many people have elevated TPO antibodies without overt thyroid dysfunction.
What a high TPO Antibodies means: causes, symptoms, next steps →Educational only — not a diagnosis. Many factors can influence a single result. Discuss anything that concerns you with a healthcare provider.
How do you get a TPO Antibodies test?
Order online, a licensed physician reviews the requisition, and you walk into a nearby lab for the draw. TPO Antibodies is available on its own or inside these panels — panels cost less per marker when you want the fuller picture.
| Option | Includes | Price |
|---|---|---|
| Thyroid Antibodies | This marker only | $51.99 |
| Hashimoto's Thyroid Panel | 3 tests | $97.99 |
| Advanced Thyroid Panel | 7 tests | $129.99 |
Quest vs. Labcorp for TPO Antibodies: which lab should you pick?
Both are CLIA-certified national labs and the result is clinically equivalent, so pick whichever location is closer. Your report will print that lab's own reference range, which can differ slightly from the table above.
| Lab | Available | Price |
|---|---|---|
| Quest Diagnostics | Yes | $51.99 |
| Labcorp | Yes | $51.99 |
| BioReference (NY & NJ) | No | — |
Need help choosing a location? Use the lab finder to see draw sites near your ZIP.
Related Thyroid biomarkers
Markers commonly tested alongside TPO Antibodies.
Frequently asked
Often reflects Hashimoto's (most common) or Graves' disease. Many people have elevated TPO antibodies without overt thyroid dysfunction. A single result above the reference range is a prompt to look closer with a clinician — often a repeat test and related markers — not a diagnosis on its own.
Ready to test your tpo antibodies?
Order in two minutes, get physician-approved, and visit a lab the same day. Starts at $51.99.