On your lab requisition: Labcorp “Thyroid Peroxidase (TPO) Ab” (test no. 006676)
The short answer
The most common test for Hashimoto's thyroiditis — measures antibodies that attack thyroid enzymes, measured from a standard blood draw. At TestWell it costs $25.99 plus a $6 lab processing fee, needs no fasting, and results post in 2–4 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp.
Hospital Lab
$150
cash pay
Other Labs
$50
+ lab fees
TestWell
$25.99
+ $6 lab processing fee
Thyroid Peroxidase (TPO) antibodies target an enzyme in the thyroid gland that plays a key role in producing thyroid hormones. Elevated TPO antibodies are the hallmark of Hashimoto's thyroiditis, the most common cause of hypothyroidism. They can be elevated years before thyroid hormone levels become abnormal.
Thyroid Peroxidase antibodies — the most sensitive single marker for autoimmune thyroid disease (Hashimoto's). Used to confirm autoimmunity when TSH is abnormal.
Anyone with subclinical or overt hypothyroidism, unexplained miscarriage or infertility, family history of autoimmune disease, or other autoimmune conditions (T1 diabetes, celiac, RA).
Sample Type
Blood draw
Fasting
Not required
Results In
2–4 business days
Performed At
Quest or Labcorp
Your Thyroid Peroxidase (TPO) Antibodies results will include values for each of the 1 biomarker tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 2–4 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you. Already have results? Analyze them with your AI assistant against our physician-reviewed ranges.
No fasting required. No special preparation needed.
A Thyroid Peroxidase (TPO) Antibodies test costs $25.99 at TestWell — $31.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the same test lists at $69.00 at Labcorp OnDemand (list prices checked Sep 12, 2026). Hospital outpatient labs typically bill around $150.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. Full cost breakdown →
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest) | $25.99 | $31.99 | Includes the one $6 lab processing fee, charged once per order |
| TestWell (drawn at Labcorp) | $26.99 | $32.99 | Labcorp's own cost for this test is higher; same order, same portal, same physician review |
| TestWell (drawn at BioReference — New York & New Jersey) | $29.99 | $35.99 | New York and New Jersey orders route to BioReference; Quest Health and Labcorp OnDemand don't take self-ordered draws in those states |
| Labcorp OnDemand (Labcorp's own site) | $69.00 | $69.00 | list price checked Sep 12, 2026 |
| Hospital outpatient lab, self-pay (typical) | $150.00 | $150.00 | Reference figure; hospital charges vary widely by facility and are often higher |
54% less than the lower lab-direct list price, for the same draw at the same lab. Lab test codes: Quest test code 5081 · Labcorp test no. 006676 · BioReference code 0412-7. Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Levels above 35 IU/mL are typically considered positive. Combined with elevated TSH, it confirms Hashimoto's. Combined with normal TSH, it means euthyroid autoimmunity — you're at higher risk of developing hypothyroidism over the next 5-10 years and should be screened annually.
Hashimoto's antibodies often appear years before TSH abnormalities. Knowing you're TPO-positive lets you screen TSH more frequently, catch dysfunction early, and consider lifestyle changes (selenium, gluten reduction in celiac) that may slow progression.
On TestWell, TPO antibodies cost $25.99. Quest Direct lists the same test at $50, walk-in hospital labs typically bill $100-150 without insurance.
No fasting required. TPO levels are stable across the day and unaffected by recent meals.
TPO alone catches the vast majority of Hashimoto's cases. Adding Thyroglobulin antibodies (the Thyroid Antibodies bundle) catches the ~5% of patients who are TPO-negative but Thyroglobulin-positive — worth it for a complete workup.
Ordered directly, a Thyroid Peroxidase (TPO) Antibodies test lists at $69.00 at Labcorp OnDemand (prices checked September 2026). TestWell orders the same test at the same Quest or Labcorp patient service centers for $25.99 — $31.99 all-in with the $6 per-order lab processing fee — paid out of pocket at checkout with no insurance, doctor's visit or draw fee; HSA and FSA cards are accepted.
Thyroid Peroxidase (TPO) Antibodies test results are typically ready in 2–4 business days after your draw at Quest or Labcorp. TestWell emails you the moment they post, and your results dashboard shows each marker against its reference range with a plain-English explanation.
Order the Thyroid Peroxidase (TPO) Antibodies test online from TestWell for $25.99 (plus a $6 per-order lab processing fee) — no doctor's visit, referral or insurance needed. A licensed physician authorizes the order, then you walk into any Quest or Labcorp patient service center near you for the draw (the lab locator on our site lists the closest ones by ZIP code), and results arrive in 2–4 business days.
The CPT code for a Thyroid Peroxidase (TPO) Antibodies test is 86376. You can order it from TestWell for $25.99 — no doctor's visit or insurance required, with results in 2–4 business days.
The Thyroid Peroxidase (TPO) Antibodies test is Quest Diagnostics test code 5081, Labcorp test number 006676 ("Thyroid Peroxidase (TPO) Ab"), BioReference code 0412-7 (CPT 86376). TestWell orders it under those codes for $25.99 at Quest, Labcorp or BioReference — no doctor's visit or insurance required, results in 2–4 business days. Codes verified against the labs' catalogs in 2026.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
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TestWell Price
$25.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Better value: the Complete Thyroid Panel
Save $10.97This test is part of the Complete Thyroid Panel — 4 tests · 5 biomarkers for $109.99, $10.97 less than à la carte.
$109.99$120.96
4 tests · 5 biomarkers
Frequently ordered together
Customers who ordered Thyroid Peroxidase (TPO) Antibodies also added these for a more complete health picture.
Not sure where to start?
Thyroid Peroxidase (TPO) Antibodies
$25.99