The short answer
A rapid hemoglobin solubility screen that detects the presence of sickle hemoglobin (HbS), measured from a standard blood draw. At TestWell it costs $45.99 plus a $6 lab processing fee, needs no fasting, and results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest.
Hospital Lab
$180
cash pay
Other Labs
$60
+ lab fees
TestWell
$45.99
+ $6 lab processing fee
Sickle cell disease is an inherited blood disorder where red blood cells become misshapen and break down, causing anemia, pain crises, and organ damage. Sickle cell trait (carrying one copy of the gene) is usually asymptomatic but important to know for family planning and certain medical situations. This is a rapid hemoglobin solubility screen that detects whether sickle hemoglobin (HbS) is present. A positive result should be confirmed with hemoglobin electrophoresis to identify the specific variant and distinguish trait from disease — see our Sickle Cell Trait Screen for electrophoresis. Screening is recommended for individuals of African, Mediterranean, Middle Eastern, or South Asian descent, or anyone with a family history of sickle cell disease.
Blood health testing evaluates your blood cells, clotting factors, and oxygen-carrying capacity to detect anemia, infection, bleeding disorders, and other hematologic conditions.
Anyone investigating unexplained fatigue, frequent infections, bruising, or as part of a routine health check.
Sample Type
Blood draw
Fasting
Not required
Results In
3–5 business days
Performed At
Quest
1 biomarker tested
Your Sickle Cell Screen results will include values for each of the 1 biomarker tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 3–5 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you. Already have results? Analyze them with your AI assistant against our physician-reviewed ranges.
No fasting required. Recent blood transfusions within the last 3 months may affect results.
A Sickle Cell Screen costs $45.99 at TestWell — $51.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Hospital outpatient labs typically bill around $180.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest) | $45.99 | $51.99 | Includes the one $6 lab processing fee, charged once per order |
| Hospital outpatient lab, self-pay (typical) | $180.00 | $180.00 | Reference figure; hospital charges vary widely by facility and are often higher |
Lab test codes: Quest test code 825. Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Most Sickle Cell Screen results are available in 3–5 business days after your specimen arrives at the lab. You'll get an email the moment results are ready, with everything viewable in your TestWell portal.
Blood draw. Sample is collected at a Quest, Labcorp, or BioReference patient service center near you, or via at-home phlebotomy where available.
On TestWell, the Sickle Cell Screen is $45.99. Quest Direct lists comparable tests at $60. Walk-in hospital labs typically bill $180 or more without insurance. Insurance is not required — pay one all-in price.
No fasting required for the Sickle Cell Screen. No fasting required. Recent blood transfusions within the last 3 months may affect results.
The Sickle Cell Screen is available at Quest patient service centers nationwide. Order online at TestWell, pick your preferred lab, and we'll generate a digital requisition for the location closest to you.
The CPT code for a Sickle Cell Screen is 85660. You can order it from TestWell for $45.99 — no doctor's visit or insurance required, with results in 3–5 business days.
The Sickle Cell Screen is Quest Diagnostics test code 825 (CPT 85660). TestWell orders it under that code for $45.99 at Quest — no doctor's visit or insurance required, results in 3–5 business days. Codes verified against the labs' catalogs in 2026.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
TestWell Price
$45.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
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Sickle Cell Screen
$45.99