Investigate the hormonal and metabolic causes of ED
The short answer
Erectile Dysfunction Panel bundles 7 tests — Testosterone, Free & Total, SHBG (Sex Hormone Binding Globulin) and Estradiol (E2) plus 4 more — for $114.99 plus one $6 lab processing fee (about $16.43 per test). Fast 8–12 hours before the draw; results post in 2–5 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp.
Other Labs
Starting at $280
+ lab fees
TestWell
$114.99
+ $6 lab processing fee
Erectile dysfunction is often a symptom of an underlying hormonal or metabolic problem. This panel investigates the most common lab-identifiable causes: low testosterone (Free & Total with SHBG to assess bioavailability), estrogen balance (estradiol — elevated levels in men can lower libido and impair erectile function), blood sugar dysfunction (A1c), cardiovascular risk (Lipid Panel), thyroid disorders (TSH), and elevated prolactin — all of which can directly impair erectile function. Identifying the root cause allows for targeted treatment rather than just managing symptoms.
Erectile dysfunction workup: Total + Free Testosterone, SHBG, Estradiol, Prolactin, TSH, A1c, Lipid Panel. Identifies hormonal, vascular, and metabolic causes of ED that are often treatable.
Men with new or worsening erectile dysfunction, especially under 50 (when underlying medical causes are more likely than age). Required pre-workup before starting PDE5 inhibitors (Viagra, Cialis) or testosterone therapy.
Sample Type
Blood draw
Fasting
Required
Results In
2–5 business days
Biomarkers
11 across 7 tests
7 individual tests · 11 biomarkers measured — each test linked so you can learn more.
Fasting for 10–12 hours recommended. Best drawn in the morning before 10 AM for accurate testosterone and prolactin. Water is okay.
What can throw off this result
Physician-reviewed “Before your test” pages — what each factor does, for how long, and what to do about it.
An Erectile Dysfunction Panel costs $114.99 at TestWell — $120.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.
| Where you order | Price | One test, all-in | Notes |
|---|---|---|---|
| TestWell (drawn at Quest or Labcorp) | $114.99 | $120.99 | Includes the one $6 lab processing fee, charged once per order |
Competitor prices are read from the linked public pages and re-checked regularly; the labs' sites may add taxes or change prices without notice.
Compare more: Quest Diagnostics price list · Labcorp price list · Quest vs Labcorp · Lab test price checker
Eight tests: Total Testosterone + Free Testosterone (T) + SHBG (hormones), Estradiol (estrogen balance — elevated E2 in men can lower libido and impair erections), Prolactin (pituitary cause), TSH (thyroid), A1c (diabetes — major ED cause), and Lipid Panel (vascular disease drives ED in older men). Together they identify the major treatable causes.
Erectile arteries are smaller than coronary arteries — they show vascular disease 3-5 years before a heart attack. New-onset ED in a man over 40 warrants a cardiovascular workup, not just a Viagra prescription. The Lipid Panel + A1c components catch the most common vascular and metabolic drivers — add the Heart Health Panel for hs-CRP and ApoB if cardiovascular risk is the main concern.
Yes. ~30% of men with ED have low testosterone contributing to the problem. PDE5 inhibitors work less well when T is low. Identifying low T first (and treating it before or alongside PDE5 inhibitors) gives better outcomes than Viagra alone.
On TestWell, the ED Panel starts at $114.99 (Quest; $149.99 at Labcorp, which prices these markers higher). Ordering the same tests separately would be about $240. Quest Direct lists comparable bundles at $280, walk-in hospital labs and urology offices typically bill $500-800 for the same biomarkers without insurance.
Yes — 9-12 hours fasting (water only) and morning draw (7-10 AM). Fasting needed for Lipid Panel and A1c; morning draw needed for accurate testosterone (which peaks early).
Then ED is likely psychological (anxiety, depression, relationship stress) or due to specific medications (SSRIs, beta-blockers, finasteride). PDE5 inhibitors usually work well in this case. Counseling or medication review with a primary care physician is the next step.
If you're 40+ with new ED, consider it. The Heart Health Panel adds ApoB, Lp(a), and additional CV markers. Some men benefit from a coronary calcium (CAC) scan as well — ED can be the first symptom of CAD.
Erectile Dysfunction Panel results are typically ready in 2–5 business days after your draw at Quest or Labcorp. TestWell emails you the moment they post, and your results dashboard shows each marker against its reference range with a plain-English explanation.
Keto and high-protein diets, oral contraceptives and estrogen and time of day can change an Erectile Dysfunction Panel result without anything being wrong. Keto and high-protein diets can raise LDL Cholesterol and HDL Cholesterol and can lower Triglycerides and Hemoglobin A1c — recheck with ApoB; discuss cardiovascular risk rather than dismissing the rise as 'diet noise'. Oral contraceptives and estrogen can raise SHBG and Triglycerides and can lower Total Testosterone and Estradiol — expected; interpret testosterone with it. Time of day can shift Total Testosterone and TSH and can raise Prolactin — draw 7–10 a.m.; confirm a low result with a second morning draw. Each factor is covered on our physician-reviewed "Before your test" pages; when one applies, the fix is usually to remove it and retest.
Order the Erectile Dysfunction Panel online from TestWell for $114.99 (plus a $6 per-order lab processing fee) — no doctor's visit, referral or insurance needed. A licensed physician authorizes the order, then you walk into any Quest or Labcorp patient service center near you for the draw (the lab locator on our site lists the closest ones by ZIP code), and results arrive in 2–5 business days.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
Starting at $280 at other labs
TestWell Price
$114.99
+ $6 lab processing fee at checkout
No insurance needed · HIPAA compliant
Individual tests that complement this panel
Erectile Dysfunction Panel
$114.99