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RDW · high result

What does a high RDW mean?

Short answer

A high RDW means red cells vary more than usual in size. It's an early sign of nutritional deficiency — iron, B12 or folate — often before hemoglobin or MCV change, and rises after transfusion, in hemolysis, liver disease and mixed anemias. A high RDW with a low MCV favors iron deficiency over thalassemia trait (which usually has a normal RDW). It is also a non-specific marker that tracks inflammation and general health in research.

Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026

What is the normal range for RDW?

  • age 18+: 11.5 – 14.5 %

Often reflects iron, B12, or folate deficiency, or recent blood loss.

Full reference table, citations and testing options: RDW biomarker page.

What are the common causes of high RDW?

  1. Iron deficiency (early), B12 or folate deficiency
  2. Mixed deficiencies, recovery from anemia
  3. Recent transfusion, hemolysis
  4. Liver disease, alcohol
  5. Chronic inflammation, heart failure

What symptoms go with high RDW?

  • None from RDW itself

What do clinicians usually check next?

  • Ferritin, B12, folate
  • Reticulocyte count and peripheral smear
  • Interpret with MCV and hemoglobin

Follow-up tests available at TestWell: Ferritin ($24.99), Folate (Vitamin B9) ($32.99).

How do you recheck RDW?

Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.

Test or panelTypePriceFastingResults
General Wellness PanelPanel · 4 tests$89.99Yes1–3 business days
Blood Clotting PanelPanel · 4 tests$149.99No3–7 business days
Baseline Anemia PanelPanel · 5 tests$74.99Yes2–4 business days
CBC with DifferentialTest · 14 biomarkers$21.99No1–3 business days

Common questions

High RDW but everything else normal — does it matter?

Often it's the first hint of a developing iron, B12 or folate deficiency, so those three tests are worth checking. On its own it doesn't need treatment.

Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.