Hospital
$400+
Other Labs
$149
TestWell
$95.99
The MTHFR gene provides instructions for making an enzyme that processes folate (vitamin B9) and regulates homocysteine levels. Variants C677T and A1298C can reduce enzyme activity by 30–70%, potentially leading to elevated homocysteine, impaired methylation, and increased risk for cardiovascular disease, neural tube defects, and recurrent pregnancy loss. This test is frequently ordered for patients with unexplained elevated homocysteine, a family history of blood clots, or recurrent miscarriages. Results can guide supplementation with methylated folate (L-methylfolate) instead of standard folic acid.
Sample Type
Blood draw
Fasting
Not required
Results In
5–7 business days
Performed By
Labcorp
2 biomarkers tested
Your MTHFR Gene Mutation Analysis results will include values for each of the 2 biomarkers tested, along with reference ranges. Results are reviewed by a licensed physician before being released to your secure portal.
If any values fall outside the normal range, your report will include guidance on what that may mean and recommended next steps. You'll receive an email notification when your results are ready, typically within 5–7 business days.
Typical reference range layout
Lab reports show where your value sits relative to established reference intervals—your physician interprets this in context for you.
No fasting or special preparation required.
TestWell Price
$95.99
No insurance needed · HIPAA compliant
Frequently ordered together
Customers who ordered MTHFR Gene Mutation Analysis also added these for a more complete health picture.
8 essential blood chemistry markers covering kidney function, blood sugar, and electrolyte balance.
$20.99
Complete blood count with white blood cell breakdown — the gold standard for overall blood health screening.
$21.99
The definitive vitamin D test — an estimated 42% of American adults are deficient.
$41.99
MTHFR Gene Mutation Analysis
$95.99