Large HDL Particle levels: what's normal, high and low
The count of large HDL particles — the HDL subclass most consistently associated with cardiovascular protection.
Medically reviewed by Youmna DiStefano, MD · Last reviewed October 2026
The short answer
Large HDL Particle is measured with a standard blood draw; no fasting is needed. TestWell offers panels that include Large HDL Particle, drawn at Quest or Labcorp. An out-of-range result is a prompt to look closer, not a diagnosis.
Testing for Large HDL Particle
This marker is reported as part of a panel rather than as a standalone test. Browse the panels that include it.
Browse tests- Units
- umol/L / µmol/L / nmol/L
- Sample
- Blood
- Fasting
- Not required
- Results
- 1–3 business days
- Labs
- Quest or Labcorp
Large HDL Particle Reference Range
These are the typical adult reference ranges used by major US labs. Your report will include the specific range used by the lab that processed your sample.
| Population | Range |
|---|
Reference ranges are educational. Always interpret your result with the specific range printed on your lab report and discuss anything outside the range with a clinician.
Have a result in hand? analyze it with your AI assistant using these reviewed ranges, or run it through our explainer. Tools: look up another marker's range · convert lab units
What your Large HDL Particle result may mean
Low large-HDL counts often accompany insulin resistance, high triglycerides and a Pattern B LDL profile.
Educational only — not a diagnosis. Many factors can influence a single result. Discuss anything that concerns you with a healthcare provider.
Related Heart Health biomarkers
Markers commonly tested alongside Large HDL Particle.
Frequently asked
What does a low Large HDL Particle mean?
Low large-HDL counts often accompany insulin resistance, high triglycerides and a Pattern B LDL profile. A single result below the reference range is a prompt to look closer with a clinician — often a repeat test and related markers — not a diagnosis on its own.
Do I need a doctor's order to test my large hdl particle?
No. TestWell's licensed physician network reviews and approves your order — usually within minutes. You can place an order online without an in-person visit or a referral from your own doctor.
How long does it take to get Large HDL Particle results?
Most Large HDL Particle results are available in 1–3 business days after your specimen arrives at the lab. You'll get an email the moment your results are ready, with everything viewable in your TestWell portal.
Where can I order a Large HDL Particle test?
TestWell offers panels that include Large HDL Particle alongside related markers. Browse our test catalog to find the panel that fits your goals.
Do I need to fast before my Large HDL Particle test?
Fasting is not required for the Large HDL Particle test. You can have your blood drawn any time of day.
Which lab will process my Large HDL Particle test?
Your test will be processed by Quest Diagnostics, Labcorp, or BioReference depending on which is closest to you and which lab carries the test. All three are CLIA-certified and trusted by hospitals nationwide. You'll choose your lab during checkout from 4,000+ locations.
Ready to test your large hdl particle?
Order in two minutes, get physician-approved, and visit a lab the same day.