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Creatinine · low result

What does a low Creatinine mean?

Short answer

A low creatinine usually reflects low muscle mass — older age, small frame, prolonged illness or malnutrition — and occasionally pregnancy (higher filtration), liver disease or a very low-protein diet. It is rarely a kidney problem in itself; it does make creatinine-based eGFR overestimate kidney function, which is where cystatin C helps.

Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026

What is the normal range for Creatinine?

  • Male, age 18+: 0.740 – 1.35 mg/dL
  • Female, age 18+: 0.590 – 1.04 mg/dL

Can reflect low muscle mass, pregnancy, or, in rare cases, severe muscle wasting.

Full reference table, citations and testing options: Creatinine biomarker page.

What are the common causes of low Creatinine?

  1. Low muscle mass: older adults, small body size, muscle-wasting conditions
  2. Pregnancy
  3. Liver disease, malnutrition, vegetarian diets
  4. Overhydration (dilution)

What symptoms go with low Creatinine?

  • None from the creatinine itself

What do clinicians usually check next?

  • Usually none; consider cystatin C if accurate kidney function matters
  • Nutrition and muscle assessment if unexpected

How do you recheck Creatinine?

Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.

Test or panelTypePriceFastingResults
Basic Metabolic PanelTest · 8 biomarkers$20.99Yes1–3 business days

Common questions

Is low creatinine dangerous?

No. It's a marker of low muscle mass rather than disease, though it can make kidney function look better than it is.

Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.