Triglyceride-Glucose (TyG) Index Calculator
The short answer
Enter fasting triglycerides and fasting glucose and the calculator returns the TyG index, ln(triglycerides × glucose ÷ 2) in mg/dL — a surrogate for insulin resistance validated against the insulin clamp. It needs only a lipid panel and a glucose, so most people already have the inputs. Population means run about 8.5–8.8; higher values track with insulin resistance and cardiometabolic risk.
- Inputs
- Fasting triglycerides · glucose
- Units
- mg/dL or mmol/L
- Population mean
- ≈ 8.5–8.8
- Cost
- Free
Enter your values to calculate.
TyG = ln( fasting triglycerides [mg/dL] × fasting glucose [mg/dL] ÷ 2 )
Educational — a derived index, not a diagnosis. Nothing you enter leaves your browser.
How the TyG index is calculated
TyG = ln( fasting triglycerides [mg/dL] × fasting glucose [mg/dL] ÷ 2 )
Worked example
| Fasting triglycerides (mg/dL) | Fasting glucose (mg/dL) | TyG index |
|---|---|---|
| 120 | 92 | 8.62 |
Falls in: Middle range.
How to read the result
| TyG index | Reads as |
|---|---|
| < 8.5 | Lower range |
| 8.5 – 9 | Middle range |
| ≥ 9 | Upper range |
Cut points reviewed by Youmna DiStefano, MD on 2026-09-26. Sources below.
Limits
TyG has no standardized clinical cut point: the original validation papers reported thresholds on a different logarithmic scale, and cohort studies define risk groups by tertiles or quartiles. Treat the bands as population context. Non-fasting triglycerides, alcohol, and triglyceride-lowering drugs all shift the result.
Sources
- Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord 2008;6:299–304. doi.org/10.1089/met.2008.0034
- Guerrero-Romero F, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab 2010;95:3347–3351. doi.org/10.1210/jc.2010-0288
- Ding X, et al. Triglyceride–glucose index and the incidence of atherosclerotic cardiovascular diseases: a meta-analysis of cohort studies. Cardiovasc Diabetol 2021;20:76. doi.org/10.1186/s12933-021-01268-9
Frequently asked questions
Why use TyG instead of HOMA-IR?
HOMA-IR needs a fasting insulin, which is not part of a standard panel and varies between lab assays. TyG uses two numbers on almost every metabolic work-up and was validated against the euglycemic clamp with similar accuracy.
Why do some sources quote a TyG cut point around 4.5?
The original validation papers reported their threshold on a different logarithmic scale, so their cut points (around 4.5–4.7) are not comparable to the ln(TG × glucose ÷ 2) convention used by most cohort studies and by this calculator, where values run 8 to 10.
Do my triglycerides have to be fasting?
Yes. Triglycerides rise sharply after eating and stay up for hours, which would inflate the index. Use a fasting lipid panel and a glucose from the same draw.
What lowers the TyG index?
Whatever lowers fasting triglycerides and glucose: weight loss, less refined carbohydrate and alcohol, more activity, and treating sleep apnea or thyroid disease when present. Because both inputs respond within weeks, TyG is a practical marker to re-check after a lifestyle change.
Which biomarkers does this tool cover?
Which tests give you these numbers?
Physician-authorized, drawn at Quest, Labcorp or BioReference. Results in 1–3 business days for most tests.