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Symptom → lab tests

What blood tests are worth checking for insomnia?

Short answer

Sleep problems have a few measurable contributors: a disrupted cortisol rhythm, thyroid dysfunction, low ferritin (linked to restless legs) and low magnesium. A focused set is morning and evening cortisol, TSH, ferritin and magnesium; the results either explain part of the problem or clear the way to sleep-focused evaluation.

Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026

When should you see a clinician instead of ordering a test?

  • Loud snoring with pauses in breathing or gasping — ask a clinician about a sleep study
  • Insomnia with depressed mood, hopelessness or thoughts of self-harm — seek help now (988 in the US)

Why these tests for insomnia and poor sleep?

Cortisol should be high in the morning and low at night; a flat or reversed pattern is associated with poor sleep and is checked with an a.m. and a p.m. draw. Hyperthyroidism causes difficulty falling and staying asleep. Low ferritin is a well-documented driver of restless legs, and magnesium supports muscle relaxation.

Sleep apnea, medications, caffeine, alcohol and mood disorders are the common non-lab causes; a sleep study, not a blood test, diagnoses apnea.

Which conditions do these tests help evaluate?

  • Insomnia & Poor Sleep Cortisol, thyroid, vitamin D and metabolic markers tied to disrupted sleep.
  • Thyroid Problems TSH, Free T4/T3 and antibodies to evaluate an under- or over-active thyroid.

Which tests, and what do they cost?

Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.

Test or panelTypePriceFastingResults
Sleep Health PanelSaves $100.93 vs ordering the tests separatelyPanel · 8 tests$129.99Yes3–5 business days
Complete Thyroid PanelSaves $10.97 vs ordering the tests separatelyPanel · 4 tests$109.99No3–7 business days
Cortisol (AM)Test$26.99No2–4 business days
Cortisol, PMTest$34.99No1–3 business days
TSH (Thyroid Stimulating Hormone)Test$26.99No1–3 business days
FerritinTest$24.99No1–3 business days
MagnesiumTest$19.99No2–4 business days
Vitamin D, 25-HydroxyTest$41.99No1–3 business days

Common questions

What time should I draw cortisol?

Morning cortisol between about 7 and 9 a.m., ideally within an hour of waking; evening cortisol in the late afternoon or early evening as the lab specifies. Note the times for your clinician.

Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.