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Fasting Insulin · high result

What does a high Fasting Insulin mean?

Short answer

High fasting insulin means the pancreas is working harder to keep glucose normal — the hallmark of insulin resistance, which precedes prediabetes and type 2 diabetes by years. Excess weight (especially abdominal), inactivity, poor sleep, PCOS, fatty liver and some medications drive it. A non-fasting sample raises insulin dramatically, so the fast has to be real.

Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026

What is the normal range for Fasting Insulin?

  • age 18+, fasting: 2.00 – 20.0 uIU/mL

Often reflects insulin resistance, prediabetes, or PCOS.

Full reference table, citations and testing options: Fasting Insulin biomarker page.

What are the common causes of high Fasting Insulin?

  1. Not fasting
  2. Insulin resistance from excess weight, inactivity, poor sleep
  3. PCOS
  4. Non-alcoholic fatty liver disease
  5. Medications: glucocorticoids, some antipsychotics
  6. Rare: insulinoma (with low glucose)

What symptoms go with high Fasting Insulin?

  • Often none
  • Weight gain around the middle, hunger soon after eating, afternoon energy crashes
  • Skin tags, darkened skin folds (acanthosis nigricans)

What do clinicians usually check next?

  • Fasting glucose and A1c (HOMA-IR can be calculated from glucose and insulin)
  • Lipid panel and liver enzymes
  • Repeat fasting if timing was uncertain

Follow-up tests available at TestWell: Lipid Panel ($24.99), Glucose ($14.99).

How do you recheck Fasting Insulin?

Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.

Test or panelTypePriceFastingResults
Diabetes Screening PanelPanel · 3 tests$59.99Yes2–5 business days
Pre-Diabetes PanelPanel · 5 tests$89.99Yes2–5 business days
Metabolism & Weight Loss PanelPanel · 8 tests$119.99Yes2–5 business days
Insulin, FastingTest$22.99Yes2–4 business days

Common questions

What fasting insulin level is high?

Reference ranges go up to about 25 µIU/mL, but many clinicians consider values above 10–15 a sign of insulin resistance, especially with a HOMA-IR above about 2.5.

Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.