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Reticulocyte Count · low result

What does a low Reticulocyte Count mean?

Short answer

A low reticulocyte count in someone with anemia means the marrow is not making enough new red cells: iron, B12 or folate deficiency before treatment, chronic kidney disease (too little erythropoietin), chronic inflammation, bone-marrow suppression by medications or infection, and primary marrow disorders such as aplastic anemia or myelodysplasia. With a normal hemoglobin, a low-normal count is simply not needed.

Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026

When does this result need same-day care?

  • Low reticulocytes with a rapidly falling hemoglobin, or with low platelets and white cells — prompt evaluation

What is the normal range for Reticulocyte Count?

  • age 18+: 30.0 – 100 10^9/L

Can reflect marrow suppression, iron/B12/folate deficiency, or kidney disease (low erythropoietin).

Full reference table, citations and testing options: Reticulocyte Count biomarker page.

What are the common causes of low Reticulocyte Count?

  1. Untreated iron, B12 or folate deficiency
  2. Chronic kidney disease (low erythropoietin)
  3. Anemia of chronic disease/inflammation, hypothyroidism
  4. Bone-marrow suppression: chemotherapy, some antibiotics and anticonvulsants, alcohol, parvovirus B19
  5. Aplastic anemia, myelodysplastic syndrome, marrow infiltration (less common)

What symptoms go with low Reticulocyte Count?

  • Fatigue, breathlessness, pallor; frequent infections or bruising if other cell lines are affected

What do clinicians usually check next?

  • Ferritin, B12, folate, kidney function, TSH
  • Peripheral smear; CBC trend
  • Hematology referral (possible marrow evaluation) when the count stays low without a nutritional or renal cause

Follow-up tests available at TestWell: CBC with Differential ($21.99), CBC (Complete Blood Count) ($21.99), TSH (Thyroid Stimulating Hormone) ($26.99), TSH + Free T4 ($27.99), Ferritin ($24.99), Folate (Vitamin B9) ($32.99).

How do you recheck Reticulocyte Count?

Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.

Test or panelTypePriceFastingResults
Comprehensive Anemia WorkupPanel · 8 tests$169.99Yes3–5 business days
Immature Red Blood Cell TestTest$19.99No1–3 business days

Common questions

What is the reticulocyte production index?

A correction of the count for how severe the anemia is. A raw count can look 'normal' while still being inadequate for a low hemoglobin; the index below 2 means under-production.

Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.