Lipoprotein(a) · high result
What does a high Lipoprotein(a) mean?
Short answer
Lipoprotein(a) is inherited and mostly fixed for life; about 1 in 5 people has a high level. Above about 125 nmol/L (or 50 mg/dL) is considered high and independently raises the risk of heart attack, stroke and aortic valve stenosis. It doesn't respond to diet or statins, so a high result changes how aggressively LDL, blood pressure and other risks are treated — and prompts testing first-degree relatives.
Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026
What is the normal range for Lipoprotein(a)?
- age 18+: 0.000 – 75.0 nmol/L
Above 75 nmol/L is associated with increased cardiovascular risk. Lp(a) is largely genetic and stable over time.
Full reference table, citations and testing options: Lipoprotein(a) biomarker page.
What are the common causes of high Lipoprotein(a)?
- Genetics (the LPA gene) — the dominant determinant
- Kidney disease (nephrotic syndrome) and hypothyroidism modestly raise it
- Menopause modestly raises it
What symptoms go with high Lipoprotein(a)?
- None — risk is silent
What do clinicians usually check next?
- No repeat needed; it's a once-in-a-lifetime test unless conditions change
- Lower LDL/ApoB more aggressively with the clinician
- Screen parents, siblings and children
- Consider coronary calcium scoring for risk refinement
Follow-up tests available at TestWell: Calcium ($26.99).
How do you recheck Lipoprotein(a)?
Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.
| Test or panel | Type | Price | Fasting | Results |
|---|---|---|---|---|
| Advanced Lipid Panel | Test · 8 biomarkers | $90.99 | Yes | 3–5 business days |
Common questions
Can I lower lipoprotein(a)?
Not meaningfully with lifestyle or statins. PCSK9 inhibitors lower it 20–30%; dedicated Lp(a)-lowering drugs are in late-stage trials. Meanwhile the strategy is to drive every other risk factor down.
Should my family be tested?
Yes — it's inherited, so first-degree relatives have a substantial chance of also being high.
Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.