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LDL/HDL Ratio · high result

What does a high LDL/HDL Ratio mean?

Short answer

An LDL/HDL ratio above 3.5 means 'bad' cholesterol outweighs 'good' by a margin associated with higher cardiovascular risk. It rises with high LDL (diet, genetics, hypothyroidism) or low HDL (insulin resistance, smoking, inactivity). The ratio is a shorthand; ApoB and non-HDL cholesterol are the numbers guidelines act on.

Medically reviewed by Youmna DiStefano, MD · Last reviewed September 2026

What is the normal range for LDL/HDL Ratio?

  • age 18+: 0.000 – 3.50 ratio

Above 3.5 suggests elevated cardiovascular risk; below 2.0 is considered ideal.

Full reference table, citations and testing options: LDL/HDL Ratio biomarker page.

What are the common causes of high LDL/HDL Ratio?

  1. High LDL: saturated-fat-heavy diet, familial hypercholesterolemia, hypothyroidism, nephrotic syndrome
  2. Low HDL: insulin resistance, smoking, inactivity, high triglycerides
  3. Anabolic steroids, some medications

What symptoms go with high LDL/HDL Ratio?

  • None

What do clinicians usually check next?

  • ApoB and Lp(a) once; A1c, TSH
  • Blood pressure and smoking status for a 10-year risk estimate
  • Repeat lipids 6–12 weeks after diet or medication changes

Follow-up tests available at TestWell: TSH (Thyroid Stimulating Hormone) ($26.99), TSH + Free T4 ($27.99).

How do you recheck LDL/HDL Ratio?

Prices are cash-pay; every order adds one $6 lab processing fee. Physician authorization is included; no insurance or referral needed.

Test or panelTypePriceFastingResults
Lipid Panel with LDL/HDL RatioTest · 5 biomarkers$24.99Yes1–3 business days

Common questions

What is a good LDL/HDL ratio?

Under 3.5 is the conventional cutoff; under 2.5 is often quoted as optimal. Guidelines now prefer ApoB or non-HDL targets over ratios because a ratio can look fine while both numbers are wrong.

Educational content, not a diagnosis. Lab results are one input; a clinician interprets them with your history and exam.