---
title: TRT Quarterly Panel
type: panel
id: trt-quarterly
url: "https://www.test-well.com/tests/trt-quarterly-panel"
price_usd: 179
lab_fee_usd: 6
all_in_usd: 185
tests_included: 11
biomarkers_measured: 40
category: Hormones
sample: Blood draw
fasting_required: true
results_in: "2–4 business days"
labs:
  - Quest
  - Labcorp
  - BioReference
orderable: true
reviewed_at: 2026-09-14
order_url: "https://www.test-well.com/cart?add=trt-quarterly-panel&utm_source=ai_agent&utm_medium=markdown"
---

# TRT Quarterly Panel

> TRT Quarterly Panel bundles 11 tests — Testosterone, Total, Testosterone, Free (Direct) and SHBG (Sex Hormone Binding Globulin) plus 8 more — for $179.00 all-in (about $16.27 per test). Fast 8–12 hours before the draw; results post in 2–4 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp.

*Quarterly monitoring labs for patients on testosterone therapy*

## Key facts

| Fact | Value |
| --- | --- |
| Price | $179.00 + $6 lab processing fee per order ($185.00 all-in) |
| Versus buying separately | $326.89 for the 11 tests individually — the panel saves 45% |
| Tests included | 11 |
| Biomarkers measured | 40 |
| Sample | Blood draw |
| Fasting | Yes — 8–12 hours |
| Results | 2–4 business days |
| Labs | Quest Diagnostics, Labcorp, BioReference (NY & NJ) |
| Physician authorization | Included — no doctor's visit, referral or insurance needed |

## What does the TRT Quarterly Panel cover?

11 essential tests for TRT monitoring every 3 months. Includes testosterone (total + free), SHBG, estradiol, LH/FSH, PSA, CBC, CMP, lipid panel, and HbA1c. Vitamin D and thyroid panel are available as optional add-ons.

The TRT Quarterly Panel is designed for patients currently on testosterone replacement therapy who need regular monitoring. It tracks testosterone levels (total and free) to confirm dosing, SHBG and estradiol to monitor aromatization, and LH and FSH to assess pituitary suppression. PSA monitors prostate health. CBC is critical for detecting polycythemia (elevated hematocrit/hemoglobin), the most common side effect of TRT. CMP, lipid panel, and HbA1c track metabolic and cardiovascular health over time. Vitamin D and a thyroid panel are available as optional add-ons below — useful for patients who want a more complete picture but not strictly required quarterly. Recommended every 3 months for the first year, then every 6 months if stable.

**Clinical use:** TRT monitoring: Total + Free Testosterone, Estradiol, SHBG, CBC (hematocrit safety), PSA, Lipid Panel. The standard every-3-month workup recommended by AUA and Endocrine Society for men on testosterone replacement.

## Who should order it?

Men currently on testosterone replacement therapy — required for safe dose management. AUA recommends quarterly monitoring in the first year, then every 6-12 months once stable.

## Tests included

| Test | Biomarkers | Standalone price | CPT |
| --- | --- | --- | --- |
| [Testosterone, Total](https://www.test-well.com/tests/testosterone-total) | 1 (Total Testosterone) | $33.99 | 84403 |
| [Testosterone, Free (Direct)](https://www.test-well.com/tests/testosterone-free) | 1 (Free Testosterone) | $33.99 | 84402 |
| [SHBG (Sex Hormone Binding Globulin)](https://www.test-well.com/tests/shbg-sex-hormone-binding-globulin) | 1 (SHBG) | $34.99 | 84270 |
| [Estradiol (E2)](https://www.test-well.com/tests/estradiol) | 1 (Estradiol) | $35.99 | 82670 |
| [LH (Luteinizing Hormone)](https://www.test-well.com/tests/luteinizing-hormone) | 1 (LH) | $36.99 | 83002 |
| [FSH (Follicle Stimulating Hormone)](https://www.test-well.com/tests/fsh) | 1 (FSH) | $29.99 | 83001 |
| [PSA, Total](https://www.test-well.com/tests/psa-total) | 1 (PSA Total) | $28.99 | 84153 |
| [CBC with Differential](https://www.test-well.com/tests/cbc-with-differential) | 14 (WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, …) | $21.99 | 85025 |
| [Comprehensive Metabolic Panel](https://www.test-well.com/tests/comprehensive-metabolic-panel) | 14 (Glucose, BUN, Creatinine, Sodium, Potassium, Chloride, …) | $22.99 | 80053 |
| [Lipid Panel](https://www.test-well.com/tests/lipid-panel) | 4 (Total Cholesterol, HDL Cholesterol, LDL Cholesterol (calculated), Triglycerides) | $24.99 | 80061 |
| [Hemoglobin A1c](https://www.test-well.com/tests/hemoglobin-a1c) | 1 (Hemoglobin A1c) | $21.99 | 83036 |

## Price by lab

| Lab | Panel price | All-in (with $6 fee) | Notes |
| --- | --- | --- | --- |
| Quest Diagnostics | $179.00 | $185.00 | Choose at checkout |
| Labcorp | $229.00 | $235.00 | Choose at checkout |
| BioReference (NY & NJ) | $229.00 | $235.00 | New York and New Jersey orders route here automatically |

## How much does a TRT Quarterly Panel cost?

A TRT Quarterly Panel costs $179.00 at TestWell — $185.00 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.

| Where you order | Price | One test, all-in | Notes |
| --- | --- | --- | --- |
| TestWell (drawn at Quest or Labcorp) | $179.00 | $185.00 | Includes the one $6 lab processing fee, charged once per order |

## How do you prepare?

Fasting for 10–12 hours is recommended. Morning blood draw (before 10 AM) preferred. If on injectable testosterone, draw blood at trough (day before next injection) for most accurate levels.

## Related conditions

- Hypogonadism, on TRT (E29.1)
- TRT-induced erythrocytosis (D75.1)
- TRT estradiol management (E29.1)

## Is the TRT Quarterly Panel worth it?

> If you're on testosterone therapy, this is the standard-of-care monitoring set in one quarterly draw: your testosterone response plus the safety markers every prescriber tracks - hematocrit (CBC), estradiol, PSA, lipids, A1c. Worth it whether your TRT comes from a men's-health clinic, telehealth, or your own physician - $179 versus ordering the eleven tests separately.

### Worth it if you…

- Anyone on TRT (injections, gels, pellets) due for quarterly labs - this is the panel prescribers ask for
- Telehealth TRT patients whose provider charges $250+ for the same quarterly monitoring set
- Self-directed patients who want objective safety data (hematocrit and PSA drift are silent) between clinic visits
- Pre-TRT baselines: drawing the full set BEFORE starting gives every later result a comparison point

### You can probably wait if you…

- You're not on (or starting) testosterone therapy - the [Free & Total + SHBG test ($69.99)](https://www.test-well.com/tests/testosterone-free-total-shbg) is the right diagnostic starting point
- Your prescriber already orders quarterly labs - duplicate draws waste money; bring this list to confirm coverage instead
- You're chasing a fertility question - TRT suppresses sperm production; that conversation needs a clinician, not more monitoring labs

### At home or in the lab?

At-home collection is not recommended for this test. One venous draw at Quest, morning preferred, fasting 10-12 hours recommended (the panel includes lipids and A1c). Time it consistently relative to your dose - for weekly injections, most draw at trough, the morning before injection day - so quarter-over-quarter trends are comparable.

### How do you read the results?

| Result | Typical adult range | What an out-of-range value can mean |
| --- | --- | --- |
| Total + free testosterone | On-therapy targets are set by your prescriber | Confirms your protocol actually achieves therapeutic levels at trough - the efficacy half of monitoring. |
| Hematocrit (from CBC) | ~38-52% (labs vary) | Testosterone stimulates red-cell production; rising hematocrit is TRT's most common side effect and the classic reason doses get adjusted. Trending it quarterly catches the drift early. |
| Estradiol, PSA, lipids, A1c | See individual reference ranges | Estradiol rises via aromatization (symptoms when out of proportion); PSA is the prostate-safety trend every guideline tracks on therapy; lipids and A1c capture the metabolic picture. |

_This section medically reviewed; last reviewed 2026-08-04._

## Common questions about the TRT Quarterly Panel

### What does the TRT Quarterly Panel check?

Total + Free T (dose effectiveness), Estradiol (aromatization), SHBG (binding fluctuations), CBC (hematocrit safety — TRT can thicken blood), PSA (prostate safety baseline), Lipid Panel (TRT can worsen lipids in some men).

### How much does the TRT Quarterly Panel cost?

On TestWell, the TRT Quarterly Panel starts at $179.00 (Quest; $229 at Labcorp or BioReference, which price these hormone markers higher) — vs about $480 at Quest Direct and $300-$700 at TRT clinics. Quarterly testing this affordable removes the cost barrier to safe monitoring.

### Do I need to fast?

Yes — morning fasting draw between 7-10 AM. Time it relative to your last TRT dose for consistency (e.g., always 3-4 days into your injection cycle).

### When should I draw relative to my last injection?

For injectable TRT (cypionate or enanthate weekly), draw at the trough — 6-7 days after last injection. For daily creams/gels, draw 2-4 hours after morning application. For pellets, draw at month 3 post-insertion (steady-state).

### What if my hematocrit is creeping up?

Hematocrit >54% raises stroke and DVT risk. Solutions: reduce TRT dose, switch from injectable to cream (less erythrocytosis), donate blood (therapeutic phlebotomy). Discuss with your TRT provider.

### How often should I get labs on TRT?

Quarterly is the common rhythm in the first year and after any protocol change, often relaxing to twice yearly once stable - your prescriber sets the exact cadence. TestWell offers this panel as a quarterly auto-renewing subscription so the retest happens without remembering.

### When should I draw relative to my injection?

Consistency beats any single 'right' answer: most prescribers want trough levels - the morning of (or day before) your next weekly injection - because peak levels vary wildly with timing. Whatever you choose, repeat it every quarter so your trend line means something.

### What does TRT monitoring cost without insurance?

$179 for the 11-test panel on TestWell - the same set ordered individually runs well over $300, and men's-health clinics commonly bill $250-400 for quarterly labs. HSA/FSA eligible.

## How to order

1. Add to cart: https://www.test-well.com/cart?add=trt-quarterly-panel&utm_source=ai_agent&utm_medium=markdown
2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA.
3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email.
4. One draw at any Quest Diagnostics, Labcorp, BioReference (NY & NJ) patient service center covers every test in the panel.
5. Results post to your TestWell portal in 2–4 business days.

## Related

- [Testosterone Testing: Which Test Do You Actually Need (Total, Free, SHBG, or Full TRT Panel)?](https://www.test-well.com/guides/testosterone-testing)
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- [Female HRT Starting Panel](https://www.test-well.com/tests/female-hrt-starting-panel) — 20 tests · $249.99
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- [Full test directory](https://www.test-well.com/tests/directory)

---

Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md

Canonical page: https://www.test-well.com/tests/trt-quarterly-panel
Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt

Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.
