--- title: STI Comprehensive Panel type: panel id: sti-comprehensive url: "https://www.test-well.com/tests/sti-comprehensive-panel" price_usd: 249.99 lab_fee_usd: 6 all_in_usd: 255.99 tests_included: 7 biomarkers_measured: 14 category: STI & Infectious Disease sample: Blood draw + Urine sample fasting_required: false results_in: "3–7 business days" labs: - Quest - Labcorp orderable: true reviewed_at: 2026-09-14 order_url: "https://www.test-well.com/cart?add=sti-comprehensive-panel&utm_source=ai_agent&utm_medium=markdown" --- # STI Comprehensive Panel > STI Comprehensive Panel bundles 7 tests — HIV 1/2 Antigen & Antibodies (4th Gen), Chlamydia & Gonorrhea (RNA, Urine) and Syphilis Test with Confirmation plus 4 more — for $249.99 all-in (about $35.71 per test). No fasting is needed; results post in 3–7 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp. *Complete peace of mind — every major STI in one order* ## Key facts | Fact | Value | | --- | --- | | Price | $249.99 + $6 lab processing fee per order ($255.99 all-in) | | Versus buying separately | $339.93 for the 7 tests individually — the panel saves 26% | | Tests included | 7 | | Biomarkers measured | 14 | | Sample | Blood draw + Urine sample | | Fasting | Not required | | Results | 3–7 business days | | Labs | Quest Diagnostics, Labcorp | | Physician authorization | Included — no doctor's visit, referral or insurance needed | ## What does the STI Comprehensive Panel cover? The most thorough STI panel available — HIV, Chlamydia, Gonorrhea, Syphilis, Herpes (HSV 1 & 2), Hepatitis B & C, and Trichomoniasis. The STI Comprehensive Panel covers every major sexually transmitted infection in a single order. It includes 4th-generation HIV testing, urine-based Chlamydia and Gonorrhea screening, Syphilis with confirmation, type-specific Herpes (HSV 1 & 2) antibodies, Hepatitis B and C screening, and Trichomoniasis testing. This is the most complete STI panel available and is recommended for anyone who wants full peace of mind or has had a new or multiple partners. **Clinical use:** Comprehensive STI screen: HIV (4th-gen), Syphilis, Chlamydia + Gonorrhea (NAAT), Hepatitis B, Hepatitis C, Herpes (HSV-1/2). The complete one-draw STI workup recommended for new partners or annual screening. ## Who should order it? Anyone with new partners, partners of someone diagnosed with an STI, anyone wanting comprehensive screening before unprotected sex, MSM annual screening, anyone wanting complete peace of mind in a single panel. ## Tests included | Test | Biomarkers | Standalone price | CPT | | --- | --- | --- | --- | | [HIV 1/2 Antigen & Antibodies (4th Gen)](https://www.test-well.com/tests/hiv-test) | 2 (HIV-1/2 Antibodies, HIV p24 Antigen) | $39.99 | 87389 | | [Chlamydia & Gonorrhea (RNA, Urine)](https://www.test-well.com/tests/chlamydia-gonorrhea) | 2 (Chlamydia trachomatis RNA, Neisseria gonorrhoeae RNA) | $52.99 | 87491, 87591 | | [Syphilis Test with Confirmation](https://www.test-well.com/tests/syphilis-test) | 2 (RPR Screen, FTA-ABS Confirmation (if reactive)) | $39.99 | 86592 | | [Herpes (HSV 1 & 2) Antibody Test](https://www.test-well.com/tests/herpes-hsv-1-2) | 2 (HSV-1 IgG Antibody, HSV-2 IgG Antibody) | $54.99 | — | | [Hepatitis B Test with Confirmation](https://www.test-well.com/tests/hepatitis-b-test) | 3 (HBsAg, HBsAb, HBcAb) | $59.99 | 87340, 86706, 86704 | | [Hepatitis C Test with Confirmation](https://www.test-well.com/tests/hepatitis-c-test) | 2 (HCV Antibody, HCV RNA (if reactive)) | $30.99 | 86803 | | [Trichomoniasis Test](https://www.test-well.com/tests/trichomoniasis) | 1 (Trichomonas vaginalis RNA) | $60.99 | — | ## Price by lab | Lab | Panel price | All-in (with $6 fee) | Notes | | --- | --- | --- | --- | | Quest Diagnostics | $249.99 | $255.99 | Choose at checkout | | Labcorp | $249.99 | $255.99 | Choose at checkout | ## How much does a STI Comprehensive Panel cost? A STI Comprehensive Panel costs $249.99 at TestWell — $255.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the closest equivalent lists at $282.00 at Quest Health and $489.00 at Labcorp OnDemand (list prices checked Sep 12, 2026; see the notes on how the products differ). With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. | Where you order | Price | One test, all-in | Notes | | --- | --- | --- | --- | | TestWell (drawn at Quest or Labcorp) | $249.99 | $255.99 | Includes the one $6 lab processing fee, charged once per order | | Quest Health (Quest Diagnostics' own site) | $282.00 | $282.00 | Infection lists differ; both are expanded STI screens · [list price checked 2026-09-12](https://www.questhealth.com/product/std-screening-panel-expanded/37328M.html) | | Labcorp OnDemand (Labcorp's own site) | $489.00 | $489.00 | Infection lists differ; both are expanded STI screens · [list price checked 2026-09-12](https://www.ondemand.labcorp.com/lab-tests/complete-sti-test) | ## How do you prepare? Do not urinate for at least 1 hour before providing urine sample. No fasting required. ## Related conditions - STI screening (routine) (Z11.3) - HIV infection (B20) - Chlamydia / Gonorrhea infection (A56.9) - Syphilis (A53.9) ## Common questions about the STI Comprehensive Panel ### What's included in the STI Comprehensive Panel? [HIV 4th-Gen](https://www.test-well.com/tests/hiv-test), [Syphilis with confirmation](https://www.test-well.com/tests/syphilis-test), [Chlamydia + Gonorrhea NAAT](https://www.test-well.com/tests/chlamydia-gonorrhea), [Hepatitis B](https://www.test-well.com/tests/hepatitis-b-test), [Hepatitis C](https://www.test-well.com/tests/hepatitis-c-test), [HSV-1 + HSV-2](https://www.test-well.com/tests/herpes-hsv-1-2). 7 individual tests covering the major bacterial, viral, and protozoal STIs. ### How is this different from the STI Basic Panel? [STI Basic Panel](https://www.test-well.com/tests/sti-basic-panel) at $85 has 3 tests (HIV, Syphilis, Hep C). Comprehensive at $249 adds Chlamydia/Gonorrhea (the two most common bacterial STIs), Hepatitis B, and Herpes — the complete workup recommended for new-partner screening or annual MSM testing. ### Should I include herpes testing? CDC actually recommends AGAINST routine HSV screening in asymptomatic adults — false-positive rates are high and the psychological cost outweighs the clinical benefit. If you've never had genital ulcers, consider ordering [STI Basic Panel](https://www.test-well.com/tests/sti-basic-panel) + [Chlamydia/Gonorrhea](https://www.test-well.com/tests/chlamydia-gonorrhea) + [Hep B](https://www.test-well.com/tests/hepatitis-b-test) instead of the full Comprehensive (which forces HSV testing). ### How soon after exposure should I test? Different timeframes per pathogen: Chlamydia/Gonorrhea (1-2 weeks), HIV 4th-gen (2-4 weeks), Syphilis (3-6 weeks), Hep B/C (8-12 weeks), HSV antibodies (4-12 weeks). For complete post-exposure screening, test initial + repeat at 6 weeks + 3 months. ### How much does the STI Comprehensive Panel cost without insurance? On TestWell, the STI Comprehensive Panel is $249.99. Ordering the same 7 tests separately would be about $340. Quest Direct lists comparable bundles at $450, walk-in hospital labs typically bill $800-1500 for the same biomarkers without insurance. Free testing is available at community health centers and Planned Parenthood for many of these. ### Is this anonymous? Your TestWell order is private — only you see your results. Positive results for reportable conditions (HIV, syphilis, gonorrhea, chlamydia) are reported by the lab to public health per state law, not by TestWell. We don't share data with insurance, employers, or partners. ### Do I need to fast? No fasting required. For the urine portion (Chlamydia/Gonorrhea NAAT), hold urination for 1-2 hours before sample collection and use first-catch (not midstream) urine. ### How often should I test? Annually for sexually active adults with stable partners. Every 3-6 months for MSM, anyone with multiple partners, or anyone using PrEP. After any new partner before unprotected sex. After any unprotected exposure with unknown-status partner. ## How to order 1. Add to cart: https://www.test-well.com/cart?add=sti-comprehensive-panel&utm_source=ai_agent&utm_medium=markdown 2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA. 3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email. 4. One draw at any Quest Diagnostics, Labcorp patient service center covers every test in the panel. 5. Results post to your TestWell portal in 3–7 business days. ## Related - [STI Basic Panel](https://www.test-well.com/tests/sti-basic-panel) — 2 tests · $84.99 - [All STI & Infectious Disease tests](https://www.test-well.com/tests/category/sti-infectious-disease) - [Full test directory](https://www.test-well.com/tests/directory) --- Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md Canonical page: https://www.test-well.com/tests/sti-comprehensive-panel Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.