--- title: Sickle Cell Screen Test type: test id: sickle-cell-screen-alc url: "https://www.test-well.com/tests/sickle-cell-screen-quest" price_usd: 45.99 lab_fee_usd: 6 all_in_usd: 51.99 cpt: 85660 category: Blood Health sample: Blood draw fasting_required: false results_in: "3–5 business days" labs: - Quest orderable: true reviewed_at: 2026-09-14 order_url: "https://www.test-well.com/cart?add=sickle-cell-screen-quest&utm_source=ai_agent&utm_medium=markdown" --- # Sickle Cell Screen Test > A rapid hemoglobin solubility screen that detects the presence of sickle hemoglobin (HbS), measured from a standard blood draw. At TestWell it costs $45.99 plus a $6 lab fee, needs no fasting, and results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest. ## Key facts | Fact | Value | | --- | --- | | Price | $45.99 + $6 lab processing fee per order ($51.99 all-in for this test alone) | | CPT code | 85660 | | Sample | Blood draw | | Fasting | Not required | | Results | 3–5 business days | | Labs | Quest Diagnostics | | Biomarkers measured | 1 | | Physician authorization | Included — no doctor's visit, referral or insurance needed | | Payment | Card, HSA or FSA; cash-pay only (no insurance billing) | ## What does the Sickle Cell Screen test tell you? A rapid hemoglobin solubility screen that detects the presence of sickle hemoglobin (HbS). Sickle cell disease is an inherited blood disorder where red blood cells become misshapen and break down, causing anemia, pain crises, and organ damage. Sickle cell trait (carrying one copy of the gene) is usually asymptomatic but important to know for family planning and certain medical situations. This is a rapid hemoglobin solubility screen that detects whether sickle hemoglobin (HbS) is present. A positive result should be confirmed with hemoglobin electrophoresis to identify the specific variant and distinguish trait from disease — see our Sickle Cell Trait Screen for electrophoresis. Screening is recommended for individuals of African, Mediterranean, Middle Eastern, or South Asian descent, or anyone with a family history of sickle cell disease. **Clinical use:** Blood health testing evaluates your blood cells, clotting factors, and oxygen-carrying capacity to detect anemia, infection, bleeding disorders, and other hematologic conditions. ## Who should order it? Anyone investigating unexplained fatigue, frequent infections, bruising, or as part of a routine health check. ## Biomarkers measured - Sickle Cell (Hemoglobin Solubility) Screen ## Price by lab | Lab | Test price | All-in (with $6 fee) | Notes | | --- | --- | --- | --- | | Quest Diagnostics | $45.99 | $51.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) | Rhode Island is not served. Prices are identical online and in the lab; no draw fee or physician fee is added. ## How much does a Sickle Cell Screen test cost? A Sickle Cell Screen test costs $45.99 at TestWell — $51.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Hospital outpatient labs typically bill around $180.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. | Where you order | Price | One test, all-in | Notes | | --- | --- | --- | --- | | TestWell (drawn at Quest or Labcorp) | $45.99 | $51.99 | Includes the one $6 lab processing fee, charged once per order | | Hospital outpatient lab, self-pay (typical) | $180.00 | $180.00 | Reference figure; hospital charges vary widely by facility and are often higher | Lab test codes: Quest test code 825. ## How do you prepare? No fasting required. Recent blood transfusions within the last 3 months may affect results. ## Related conditions - [Anemia](https://www.test-well.com/conditions/anemia) (D64.9) - Hematologic disorder (D75.9) ## Common questions about the Sickle Cell Screen test ### How long do Sickle Cell Screen results take? Most Sickle Cell Screen results are available in 3–5 business days after your specimen arrives at the lab. You'll get an email the moment results are ready, with everything viewable in your TestWell portal. ### What sample is collected for the Sickle Cell Screen? Blood draw. Sample is collected at a Quest, Labcorp, or BioReference patient service center near you, or via at-home phlebotomy where available. ### How much does the Sickle Cell Screen cost without insurance? On TestWell, the Sickle Cell Screen is $45.99. Quest Direct lists comparable tests at $60. Walk-in hospital labs typically bill $180 or more without insurance. Insurance is not required — pay one all-in price. ### Do I need to fast before the Sickle Cell Screen? No fasting required for the Sickle Cell Screen. No fasting required. Recent blood transfusions within the last 3 months may affect results. ### Where can I get the Sickle Cell Screen done? The Sickle Cell Screen is available at Quest patient service centers nationwide. Order online at TestWell, pick your preferred lab, and we'll generate a digital requisition for the location closest to you. ## How to order 1. Add to cart: https://www.test-well.com/cart?add=sickle-cell-screen-quest&utm_source=ai_agent&utm_medium=markdown 2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA. 3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email. 4. Walk into any Quest Diagnostics patient service center — no appointment needed at most sites. 5. Results post to your TestWell portal in 3–5 business days with reference ranges and flags. ## Related - [D-Dimer](https://www.test-well.com/tests/d-dimer) — $69.99 - [Factor V Leiden Mutation](https://www.test-well.com/tests/factor-v-leiden) — $131.99 - [Haptoglobin](https://www.test-well.com/tests/haptoglobin-test) — $101.99 - [Immature Red Blood Cell Test](https://www.test-well.com/tests/reticulocyte-count) — $19.99 - [Prothrombin Time with INR](https://www.test-well.com/tests/prothrombin-time-inr) — $23.99 - [All Blood Health tests](https://www.test-well.com/tests/category/blood-health) - [Full test directory](https://www.test-well.com/tests/directory) --- Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md Canonical page: https://www.test-well.com/tests/sickle-cell-screen-quest Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.