---
title: Metabolism & Weight Loss Panel
type: panel
id: metabolism-panel
url: "https://www.test-well.com/tests/metabolism-panel"
price_usd: 119.99
lab_fee_usd: 6
all_in_usd: 125.99
tests_included: 8
biomarkers_measured: 24
category: Metabolic Health
sample: Blood draw
fasting_required: true
results_in: "2–5 business days"
labs:
  - Quest
  - Labcorp
orderable: true
reviewed_at: 2026-09-14
order_url: "https://www.test-well.com/cart?add=metabolism-panel&utm_source=ai_agent&utm_medium=markdown"
---

# Metabolism & Weight Loss Panel

> Metabolism & Weight Loss Panel bundles 8 tests — Comprehensive Metabolic Panel, Lipid Panel and TSH (Thyroid Stimulating Hormone) plus 5 more — for $119.99 all-in (about $15.00 per test). Fast 8–12 hours before the draw; results post in 2–5 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp.

*The lab roadmap for your weight loss journey*

## Key facts

| Fact | Value |
| --- | --- |
| Price | $119.99 + $6 lab processing fee per order ($125.99 all-in) |
| Versus buying separately | $225.92 for the 8 tests individually — the panel saves 47% |
| Tests included | 8 |
| Biomarkers measured | 24 |
| Sample | Blood draw |
| Fasting | Yes — 8–12 hours |
| Results | 2–5 business days |
| Labs | Quest Diagnostics, Labcorp |
| Physician authorization | Included — no doctor's visit, referral or insurance needed |

## What does the Metabolism & Weight Loss Panel cover?

Comprehensive metabolic assessment covering thyroid, blood sugar, insulin resistance, cortisol, leptin, and key nutrient levels.

The Metabolism & Weight Loss Panel targets every major metabolic pathway that affects body weight. It evaluates organ function (CMP), cardiovascular risk (Lipid Panel), thyroid output (TSH), blood sugar control (A1c), early insulin resistance (Fasting Insulin), stress hormones (Cortisol), satiety signaling (Leptin), and vitamin D — which influences metabolism and energy. This panel gives you and your provider a complete metabolic roadmap before starting or adjusting a weight loss program.

**Clinical use:** Metabolic-health deep dive: CMP, Lipid Panel, A1c, Fasting Insulin, TSH, Cortisol AM, Leptin, Vitamin D. Detects insulin resistance plus the thyroid, stress, and satiety-signaling contributors behind weight regulation before they become clinical disease.

## Who should order it?

Anyone with central obesity, family history of T2D or heart disease, prediabetes management, athletes optimizing performance, longevity protocols, GLP-1 patients tracking response.

## Tests included

| Test | Biomarkers | Standalone price | CPT |
| --- | --- | --- | --- |
| [Comprehensive Metabolic Panel](https://www.test-well.com/tests/comprehensive-metabolic-panel) | 14 (Glucose, BUN, Creatinine, Sodium, Potassium, Chloride, …) | $22.99 | 80053 |
| [Lipid Panel](https://www.test-well.com/tests/lipid-panel) | 4 (Total Cholesterol, HDL Cholesterol, LDL Cholesterol (calculated), Triglycerides) | $24.99 | 80061 |
| [TSH (Thyroid Stimulating Hormone)](https://www.test-well.com/tests/tsh) | 1 (TSH) | $26.99 | 84443 |
| [Hemoglobin A1c](https://www.test-well.com/tests/hemoglobin-a1c) | 1 (Hemoglobin A1c) | $21.99 | 83036 |
| [Insulin, Fasting](https://www.test-well.com/tests/insulin-fasting) | 1 (Insulin) | $22.99 | 83525 |
| [Cortisol (AM)](https://www.test-well.com/tests/cortisol-am) | 1 (Cortisol) | $26.99 | 82533 |
| [Leptin](https://www.test-well.com/tests/leptin) | 1 (Leptin) | $36.99 | — |
| [Vitamin D, 25-Hydroxy](https://www.test-well.com/tests/vitamin-d) | 1 (25-Hydroxy Vitamin D) | $41.99 | 82306 |

## Price by lab

| Lab | Panel price | All-in (with $6 fee) | Notes |
| --- | --- | --- | --- |
| Quest Diagnostics | $119.99 | $125.99 | Choose at checkout |
| Labcorp | $119.99 | $125.99 | Choose at checkout |

## How much does a Metabolism & Weight Loss Panel cost?

A Metabolism & Weight Loss Panel costs $119.99 at TestWell — $125.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.

| Where you order | Price | One test, all-in | Notes |
| --- | --- | --- | --- |
| TestWell (drawn at Quest or Labcorp) | $119.99 | $125.99 | Includes the one $6 lab processing fee, charged once per order |

## How do you prepare?

Fasting for 10–12 hours required. Morning draw before 10 AM preferred for accurate cortisol. Water is okay.

## Related conditions

- Metabolic syndrome (E88.81)
- Insulin resistance (E88.81)
- [Prediabetes](https://www.test-well.com/conditions/diabetes-screening) (R73.03)
- Non-alcoholic fatty liver disease (K76.0)


## Common questions about the Metabolism & Weight Loss Panel

### What's included in the Metabolism Panel?

[CMP](https://www.test-well.com/tests/comprehensive-metabolic-panel) (glucose, electrolytes, liver + kidney), [Lipid Panel](https://www.test-well.com/tests/lipid-panel), [A1c](https://www.test-well.com/tests/hemoglobin-a1c) and [Fasting Insulin](https://www.test-well.com/tests/insulin-fasting) (insulin resistance), [TSH](https://www.test-well.com/tests/tsh) (thyroid output), [Cortisol AM](https://www.test-well.com/tests/cortisol-am) (stress hormone), [Leptin](https://www.test-well.com/tests/leptin) (satiety signaling), and [Vitamin D](https://www.test-well.com/tests/vitamin-d). About 20 individual biomarkers covering the metabolic-syndrome pillars.

### How is this different from the Diabetes Panel?

[Diabetes Panel](https://www.test-well.com/tests/diabetes-screening-panel) focuses on glucose (3 tests: A1c, Glucose, Insulin). Metabolism Panel adds lipid, thyroid (TSH), stress (Cortisol AM), satiety (Leptin), and vitamin D markers on top of the liver + kidney chemistries in CMP — capturing the broader metabolic picture. Use Diabetes Panel for prediabetes screening alone; Metabolism Panel for a full metabolic-health evaluation.

### What does fatty liver have to do with metabolism?

Non-alcoholic fatty liver disease (NAFLD) is now called MASLD (Metabolic dysfunction-Associated Steatotic Liver Disease) because it's driven by insulin resistance. Elevated [ALT](https://www.test-well.com/tests/alt) with normal alcohol intake is often the earliest sign of metabolic dysfunction — especially in lean people with insulin resistance.

### How much does the Metabolism Panel cost without insurance?

On TestWell, the Metabolism Panel is $119.99. Ordering the same tests separately would be about $180. Quest Direct lists comparable bundles at $310, walk-in hospital labs typically bill $600-900 for the same biomarkers without insurance.

### What's the calculation for insulin resistance (HOMA-IR)?

HOMA-IR = (Fasting Insulin × Fasting Glucose) / 405. Values under 1.0 are optimal; 1.0-2.0 is normal; 2.0-2.5 suggests insulin resistance; above 2.5 is established insulin resistance. This calculation requires both Fasting Glucose and Fasting Insulin (both included in this panel).

### Do I need to fast?

Yes — 9-12 hours of fasting (water only) is required for accurate fasting glucose (in the [CMP](https://www.test-well.com/tests/comprehensive-metabolic-panel)), [Fasting Insulin](https://www.test-well.com/tests/insulin-fasting), and [Lipid Panel](https://www.test-well.com/tests/lipid-panel) results.

### Should I add this to a hormone panel?

Yes if you have hormonal symptoms with metabolic concerns. The pattern of low testosterone + insulin resistance + central obesity is common in men. PCOS in women involves hormonal + metabolic factors. Add [Men's Hormone Panel](https://www.test-well.com/tests/mens-hormone-panel) or [Women's Hormone Panel](https://www.test-well.com/tests/womens-hormone-panel) for the complete picture.

### How often should I retest?

Annually as baseline for adults 30+. Every 3-6 months during active metabolic interventions (diet, exercise, GLP-1, statin). Every 3 months on GLP-1 medications.

## How to order

1. Add to cart: https://www.test-well.com/cart?add=metabolism-panel&utm_source=ai_agent&utm_medium=markdown
2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA.
3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email.
4. One draw at any Quest Diagnostics, Labcorp patient service center covers every test in the panel.
5. Results post to your TestWell portal in 2–5 business days.

## Related

- [Gout Panel](https://www.test-well.com/tests/gout-panel) — 3 tests · $62.99
- [GLP-1 Monitoring & Weight Management](https://www.test-well.com/tests/glp1-monitoring-panel) — 10 tests · $169.99
- [All Metabolic Health tests](https://www.test-well.com/tests/category/metabolic-health)
- [Full test directory](https://www.test-well.com/tests/directory)

---

Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md

Canonical page: https://www.test-well.com/tests/metabolism-panel
Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt

Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.
