--- title: HIV 1/2 Antigen & Antibodies (4th Gen) Test type: test id: hiv url: "https://www.test-well.com/tests/hiv-test" price_usd: 39.99 lab_fee_usd: 6 all_in_usd: 45.99 cpt: 87389 category: STI & Infectious Disease sample: Blood draw fasting_required: false results_in: "1–4 business days" labs: - Labcorp - BioReference orderable: true reviewed_at: 2026-09-14 order_url: "https://www.test-well.com/cart?add=hiv-test&utm_source=ai_agent&utm_medium=markdown" --- # HIV 1/2 Antigen & Antibodies (4th Gen) Test > HIV 1/2 Antigen & Antibodies (4th Gen) measures HIV-1/2 Antibodies and HIV p24 Antigen from a standard blood draw. At TestWell it costs $39.99 plus a $6 lab fee, needs no fasting, and results post in 1–4 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Labcorp. ## Key facts | Fact | Value | | --- | --- | | Price | $39.99 + $6 lab processing fee per order ($45.99 all-in for this test alone) | | CPT code | 87389 | | Sample | Blood draw | | Fasting | Not required | | Results | 1–4 business days | | Labs | Labcorp, BioReference (NY & NJ) | | Biomarkers measured | 2 | | Physician authorization | Included — no doctor's visit, referral or insurance needed | | Payment | Card, HSA or FSA; cash-pay only (no insurance billing) | ## What does the HIV 1/2 Antigen & Antibodies (4th Gen) test tell you? Fourth-generation HIV test — detects both HIV antibodies and p24 antigen for earlier detection. The fourth-generation HIV test detects both HIV-1/HIV-2 antibodies and the p24 antigen, allowing for earlier detection than antibody-only tests. It can detect HIV as early as 2–4 weeks after exposure (compared to 3–12 weeks for older tests). This is the CDC-recommended screening method for all adults aged 15–65. The test includes reflexes to confirmatory testing if the screen is positive. **Clinical use:** 4th-generation HIV test detects both HIV antibodies and the p24 antigen — catches infection as early as 2-4 weeks post-exposure. Recommended annual screening per CDC for at-risk adults; one-time screening for all adults 18-65. ## Who should order it? Any sexually active adult per CDC routine-screening guidance, anyone with new partners, post-exposure screening (3 weeks after exposure for 4th-gen testing), routine MSM testing every 3-6 months, anyone with symptoms of acute HIV (flu-like illness 2-4 weeks after exposure). ## Biomarkers measured - HIV-1/2 Antibodies - HIV p24 Antigen ## Price by lab | Lab | Test price | All-in (with $6 fee) | Notes | | --- | --- | --- | --- | | Labcorp | $39.99 | $45.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) | | BioReference (NY & NJ) | $33.99 | $39.99 | New York and New Jersey orders route here automatically | Rhode Island is not served. Prices are identical online and in the lab; no draw fee or physician fee is added. ## How much does a HIV 1/2 Antigen & Antibodies (4th Gen) test cost? A HIV 1/2 Antigen & Antibodies (4th Gen) test costs $39.99 at TestWell — $45.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the closest equivalent lists at $85.00 at Quest Health and $99.00 at Labcorp OnDemand (list prices checked Sep 12, 2026; see the notes on how the products differ). Hospital outpatient labs typically bill around $150.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. | Where you order | Price | One test, all-in | Notes | | --- | --- | --- | --- | | TestWell (drawn at Quest or Labcorp) | $39.99 | $45.99 | Includes the one $6 lab processing fee, charged once per order | | Quest Health (Quest Diagnostics' own site) | $85.00 | $85.00 | Both are 4th-generation antigen/antibody screens with confirmation · [list price checked 2026-09-12](https://www.questhealth.com/product/hiv-1-2-test-with-confirmation/91431M.html) | | Labcorp OnDemand (Labcorp's own site) | $99.00 | $99.00 | [list price checked 2026-09-12](https://www.ondemand.labcorp.com/lab-tests/hiv-test) | | Hospital outpatient lab, self-pay (typical) | $150.00 | $150.00 | Reference figure; hospital charges vary widely by facility and are often higher | Lab test codes: Quest test code 91431 · Labcorp test no. 083935 · BioReference code B688-3. ## How do you prepare? No fasting required. No special preparation needed. Window period: 2–4 weeks after exposure. ## Related conditions - HIV infection (B20) - Acute HIV (B20) - Asymptomatic HIV (Z21) - HIV exposure (Z20.6) ## Common questions about the HIV 1/2 Antigen & Antibodies (4th Gen) test ### What does a 4th-generation HIV test detect? Both HIV antibodies (your immune response, takes 4-12 weeks to develop) and the p24 antigen (a viral protein detectable 2-4 weeks after infection). 4th-gen testing closes the 'window period' significantly vs older antibody-only tests — catches most acute infections at 2-4 weeks vs 3 months. ### How soon after exposure should I test? 4th-gen testing detects most infections by 2-4 weeks post-exposure. CDC recommends initial test at 2-4 weeks, repeat at 6 weeks and 3 months for a definitive result. PEP (post-exposure prophylaxis) is most effective within 72 hours — go to urgent care immediately if recent exposure. ### What if my test is positive? All TestWell HIV tests use a confirmatory algorithm — a reactive screen automatically triggers a confirmatory Western blot or HIV-1/2 differentiation test before reporting positive. Effective treatment makes HIV a manageable chronic condition with near-normal life expectancy. We'll connect you with care providers and resources. ### How much does an HIV test cost without insurance? On TestWell, the HIV 4th-Gen test is $39.99. Quest Direct lists the same test at $55, walk-in hospital labs typically bill $100-150 without insurance. Free testing is also available at most community health centers and Planned Parenthood — check your state's options. ### What is the CPT code for an HIV test? The CPT code for 4th-generation HIV-1/2 antigen/antibody screen is 87389. Confirmatory testing uses additional codes (87534 for HIV-1 RNA, 86703 for confirmation). ### Do I need to fast? No fasting required. Any time of day is fine. ### Should I get a full STI panel instead? Yes if you haven't been tested recently or have a new partner. The [STI Comprehensive Panel](https://www.test-well.com/tests/sti-comprehensive-panel) bundles HIV with [chlamydia & gonorrhea](https://www.test-well.com/tests/chlamydia-gonorrhea), [syphilis](https://www.test-well.com/tests/syphilis-test), [hepatitis B](https://www.test-well.com/tests/hepatitis-b-test), and [hepatitis C](https://www.test-well.com/tests/hepatitis-c-test) at a discount. ## How to order 1. Add to cart: https://www.test-well.com/cart?add=hiv-test&utm_source=ai_agent&utm_medium=markdown 2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA. 3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email. 4. Walk into any Labcorp, BioReference (NY & NJ) patient service center — no appointment needed at most sites. 5. Results post to your TestWell portal in 1–4 business days with reference ranges and flags. ## Related - [STI Basic Panel](https://www.test-well.com/tests/sti-basic-panel) — 2 tests · $84.99 - [STI Comprehensive Panel](https://www.test-well.com/tests/sti-comprehensive-panel) — 7 tests · $249.99 - [Early Pregnancy Panel](https://www.test-well.com/tests/prenatal-screening-panel) — 9 tests · $249.99 - [CMV IgG + IgM Antibodies (Cytomegalovirus)](https://www.test-well.com/tests/cmv-igg-igm-antibodies) — $74.99 - [CMV IgG Antibody (Cytomegalovirus)](https://www.test-well.com/tests/cmv-igg-antibody) — $40.99 - [CMV IgM Antibody (Cytomegalovirus)](https://www.test-well.com/tests/cmv-igm-antibody) — $40.99 - [Hepatitis B Test with Confirmation](https://www.test-well.com/tests/hepatitis-b-test) — $59.99 - [Hepatitis C Test with Confirmation](https://www.test-well.com/tests/hepatitis-c-test) — $30.99 - [All STI & Infectious Disease tests](https://www.test-well.com/tests/category/sti-infectious-disease) - [Full test directory](https://www.test-well.com/tests/directory) --- Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md Canonical page: https://www.test-well.com/tests/hiv-test Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.