---
title: Estrone (E1) Test
type: test
id: estrone
url: "https://www.test-well.com/tests/estrone"
price_usd: 49.99
lab_fee_usd: 6
all_in_usd: 55.99
cpt: 82679
category: Hormones
sample: Blood draw
fasting_required: false
results_in: "3–6 business days"
labs:
  - Quest
  - Labcorp
  - BioReference
orderable: true
reviewed_at: 2026-11-02
order_url: "https://www.test-well.com/cart?add=estrone&utm_source=ai_agent&utm_medium=markdown"
---

# Estrone (E1) Test

> Estrone (E1) — the estrogen that takes over after menopause, measured from a standard blood draw. At TestWell it costs $49.99 plus a $6 lab processing fee, needs no fasting, and results post in 3–6 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp.

## Key facts

| Fact | Value |
| --- | --- |
| Price | $49.99 + $6 lab processing fee per order ($55.99 all-in for this test alone) |
| CPT code | 82679 |
| Sample | Blood draw |
| Fasting | Not required |
| Results | 3–6 business days |
| Labs | Quest Diagnostics, Labcorp, BioReference (NY & NJ) |
| Biomarkers measured | 1 |
| Physician authorization | Included — no doctor's visit, referral or insurance needed |
| Payment | Card, HSA or FSA; cash-pay only (no insurance billing) |

## What does the Estrone (E1) test tell you?

Estrone (E1) — the estrogen that takes over after menopause. Made mostly from adrenal androgens in fat tissue, it is the one to measure when estradiol alone doesn't explain symptoms, bleeding after menopause, or estrogen excess in men.

Estrone is one of the body's three main estrogens, alongside estradiol (E2) and estriol (E3). Before menopause it is a minor player: the ovaries make estradiol, and estrone mostly serves as a precursor that is converted into it. After menopause the ovaries stop, and estrone becomes the dominant estrogen — produced not by the ovaries but by the conversion of androstenedione, an adrenal androgen, in fat tissue by the enzyme aromatase. That is why estrone runs higher in people with more body fat, and why a postmenopausal woman can have a near-zero estradiol and still carry a meaningful estrogen load. Clinicians order estrone in a few situations: postmenopausal bleeding, where the question is whether peripheral estrogen production is stimulating the uterine lining; menopausal hormone therapy, especially oral estrogens, which are converted to estrone in the liver and raise E1 far more than E2, so the ratio tells you something about how the hormone is being delivered; estrogen excess in men, including breast tissue growth, where aromatase activity rather than testicular estradiol is often the source; and broader hormone workups — irregular or absent periods, PCOS, fertility — where estrone rounds out the estradiol picture. An estrone-to-estradiol ratio above one is also one of the markers of the menopausal transition. Results are reported in pg/mL against age- and cycle-specific ranges from the performing lab; the two labs we route to use different methods (Quest runs estrone by LC-MS/MS, Labcorp by immunoassay), so if you are tracking the number over time, repeat it at the same lab.

## Biomarkers measured

- Estrone

## Price by lab

| Lab | Test price | All-in (with $6 fee) | Notes |
| --- | --- | --- | --- |
| Quest Diagnostics | $49.99 | $55.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) |
| Labcorp | $49.99 | $55.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) |
| BioReference (NY & NJ) | $49.99 | $55.99 | New York and New Jersey orders route here automatically |

Rhode Island is not served. Prices are identical online and in the lab; no draw fee or physician fee is added.

## How much does an Estrone (E1) test cost?

An Estrone (E1) test costs $49.99 at TestWell — $55.99 all-in, since the $6 lab processing fee is charged once per order and there is no draw or physician fee. Hospital outpatient labs typically bill around $180.00 self-pay. With insurance you pay your plan's negotiated rate against your deductible; TestWell's price is fixed before the draw and HSA/FSA-eligible.

| Where you order | Price | One test, all-in | Notes |
| --- | --- | --- | --- |
| TestWell (drawn at Quest or Labcorp) | $49.99 | $55.99 | Includes the one $6 lab processing fee, charged once per order |
| TestWell (drawn at BioReference — New York & New Jersey) | $49.99 | $55.99 | New York and New Jersey orders route to BioReference; Quest Health and Labcorp OnDemand don't take self-ordered draws in those states |
| Hospital outpatient lab, self-pay (typical) | $180.00 | $180.00 | Reference figure; hospital charges vary widely by facility and are often higher |

Lab test codes: Quest test code 23244 · Labcorp test no. 004564 · BioReference code J259-3.

## How do you prepare?

No fasting required. If you still have a menstrual cycle, note the cycle day — ranges differ across the cycle. If you take estrogen therapy, draw at the same point in your dosing schedule each time (for oral estrogen, ideally before the day's dose). Not for use during pregnancy. For trend tracking, repeat at the same lab: Quest and Labcorp use different methods and their numbers are not interchangeable.


## Common questions about the Estrone (E1) test

### How long does it take to get Estrone (E1) test results?

Estrone (E1) test results are typically ready in 3–6 business days after your draw at Quest or Labcorp. TestWell emails you the moment they post, and your results dashboard shows each marker against its reference range with a plain-English explanation.

### Do I need to fast, or can I eat before an Estrone (E1) test?

No, fasting is not required for an Estrone (E1) test — you can eat normally and book any time of day. If you still have a menstrual cycle, note the cycle day — ranges differ across the cycle. If you take estrogen therapy, draw at the same point in your dosing schedule each time (for oral estrogen, ideally before the day's dose). Not for use during pregnancy. For trend tracking, repeat at the same lab: Quest and Labcorp use different methods and their numbers are not interchangeable.

### Where can I get an Estrone (E1) test near me without a doctor?

Order the Estrone (E1) test online from TestWell for $49.99 (plus a $6 per-order lab processing fee) — no doctor's visit, referral or insurance needed. A licensed physician authorizes the order, then you walk into any Quest or Labcorp patient service center near you for the draw (the lab locator on our site lists the closest ones by ZIP code), and results arrive in 3–6 business days.

### What is the CPT code for an Estrone (E1) test?

CPT 82679. That is the billing code Quest, Labcorp and hospital laboratories all use for an Estrone (E1) test, so it is the number to match on an explanation of benefits, a doctor's order or a price list — the same code, the same test, whichever lab draws it. You do not need the code to order: TestWell sells the Estrone (E1) test for $49.99 with the physician order included, no insurance required, and results in 3–6 business days.

### What are the Quest, Labcorp and BioReference test codes for an Estrone (E1) test?

The Estrone (E1) test is Quest Diagnostics test code 23244, Labcorp test number 004564, BioReference code J259-3 (CPT 82679). TestWell orders it under those codes for $49.99 at Quest, Labcorp or BioReference — no doctor's visit or insurance required, results in 3–6 business days. Codes verified against the labs' catalogs in 2026.

## How to order

1. Add to cart: https://www.test-well.com/cart?add=estrone&utm_source=ai_agent&utm_medium=markdown
2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA.
3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email.
4. Walk into any Quest Diagnostics, Labcorp, BioReference (NY & NJ) patient service center — no appointment needed at most sites.
5. Results post to your TestWell portal in 3–6 business days with reference ranges and flags.

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---

Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-11-02. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md

Canonical page: https://www.test-well.com/tests/estrone
Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt

Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.
