---
title: Estradiol (E2) Test
type: test
id: estradiol
url: "https://www.test-well.com/tests/estradiol"
price_usd: 35.99
lab_fee_usd: 6
all_in_usd: 41.99
cpt: 82670
category: Fertility
sample: Blood draw
fasting_required: false
results_in: "1–3 business days"
labs:
  - Quest
  - Labcorp
  - BioReference
orderable: true
reviewed_at: 2026-09-14
order_url: "https://www.test-well.com/cart?add=estradiol&utm_source=ai_agent&utm_medium=markdown"
---

# Estradiol (E2) Test

> The primary form of estrogen — essential for reproductive health, bone density, and menopause assessment, measured from a standard blood draw. At TestWell it costs $35.99 plus a $6 lab fee, needs no fasting, and results post in 1–3 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp.

## Key facts

| Fact | Value |
| --- | --- |
| Price | $35.99 + $6 lab processing fee per order ($41.99 all-in for this test alone) |
| CPT code | 82670 |
| Sample | Blood draw |
| Fasting | Not required |
| Results | 1–3 business days |
| Labs | Quest Diagnostics, Labcorp, BioReference (NY & NJ) |
| Biomarkers measured | 1 |
| Physician authorization | Included — no doctor's visit, referral or insurance needed |
| Payment | Card, HSA or FSA; cash-pay only (no insurance billing) |

## What does the Estradiol (E2) test tell you?

The primary form of estrogen — essential for reproductive health, bone density, and menopause assessment.

Estradiol (E2) is the most potent and prevalent form of estrogen in premenopausal women. It plays a critical role in menstrual cycle regulation, bone health, cholesterol metabolism, and reproductive function. Testing estradiol helps evaluate fertility, menstrual irregularities, menopause status, and hormone therapy. In men, elevated estradiol can cause gynecomastia and other symptoms.

**Clinical use:** Primary estrogen in reproductive-age women. Used to evaluate ovarian function, menstrual irregularities, fertility, and menopausal status. Also monitored in men on TRT to track aromatization.

## Who should order it?

Women with irregular periods, infertility workup, suspected perimenopause/menopause, or monitoring HRT. Men on TRT to monitor aromatization to estrogen.

## Biomarkers measured

- [Estradiol](https://www.test-well.com/biomarkers/estradiol)

## Price by lab

| Lab | Test price | All-in (with $6 fee) | Notes |
| --- | --- | --- | --- |
| Quest Diagnostics | $35.99 | $41.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) |
| Labcorp | $56.99 | $62.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) |
| BioReference (NY & NJ) | $42.99 | $48.99 | New York and New Jersey orders route here automatically |

Rhode Island is not served. Prices are identical online and in the lab; no draw fee or physician fee is added.

## How much does a Estradiol (E2) test cost?

A Estradiol (E2) test costs $35.99 at TestWell — $41.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the same test lists at $79.00 at Labcorp OnDemand (list prices checked Sep 12, 2026). Hospital outpatient labs typically bill around $200.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.

| Where you order | Price | One test, all-in | Notes |
| --- | --- | --- | --- |
| TestWell (drawn at Quest or Labcorp) | $35.99 | $41.99 | Includes the one $6 lab processing fee, charged once per order |
| Labcorp OnDemand (Labcorp's own site) | $79.00 | $79.00 | [list price checked 2026-09-12](https://www.ondemand.labcorp.com/lab-tests/estradiol-test) |
| Hospital outpatient lab, self-pay (typical) | $200.00 | $200.00 | Reference figure; hospital charges vary widely by facility and are often higher |

Lab test codes: Quest test code 4021 · Labcorp test no. 004515 · BioReference code 0516-5.

## How do you prepare?

No fasting required. Women: best tested on day 3 of the menstrual cycle for fertility evaluation.

## Related conditions

- [PCOS](https://www.test-well.com/conditions/pcos) (E28.2)
- Menopause (N95.1)
- Premature ovarian insufficiency (E28.310)
- Female infertility (N97.9)


## Common questions about the Estradiol (E2) test

### When in my cycle should I test Estradiol?

Day 3 of your cycle (counting day 1 as the first full day of bleeding) is the standard for ovarian-reserve evaluation — pair with [FSH](https://www.test-well.com/tests/fsh) for a complete reserve picture. Mid-cycle (day 13-15) for ovulation tracking. Random for menopause assessment.

### What's a normal estradiol level?

Reproductive-age women: 30-400 pg/mL depending on cycle phase (lowest in early follicular, peaks 200-400 at mid-cycle). Postmenopausal: under 30 pg/mL. Men: 10-40 pg/mL. On TRT, target 20-30 pg/mL.

### Why test estradiol on TRT?

Testosterone aromatizes (converts) to estradiol. Elevated estradiol on TRT can cause water retention, gynecomastia, mood swings, and breast tenderness. Monitor every 3 months while titrating TRT dose; add an aromatase inhibitor only if symptomatic and labs confirm elevation.

### How much does an estradiol test cost without insurance?

On TestWell, Estradiol is $35.99. Quest Direct lists the same test at $79, walk-in hospital labs typically bill $150-200 without insurance. Same CLIA-certified labs, same biomarker — TestWell just removes the markup.

### What is the CPT code for an estradiol test?

The CPT code for estradiol (E2) is 82670. Most fertility/hormone workups bill 82670 alongside 83001 (FSH) and 83002 (LH).

### Do I need to fast for an estradiol test?

No fasting required. But timing within the menstrual cycle matters more than fasting state — check your last menstrual period date before drawing.

### Should I test estradiol with other hormones?

Yes. For fertility workup, pair with [FSH](https://www.test-well.com/tests/fsh), [LH](https://www.test-well.com/tests/luteinizing-hormone), [AMH](https://www.test-well.com/tests/amh), [progesterone](https://www.test-well.com/tests/progesterone), [prolactin](https://www.test-well.com/tests/prolactin). The [Women's Hormone Panel](https://www.test-well.com/tests/womens-hormone-panel) bundles the core fertility hormones at a discount.

## How to order

1. Add to cart: https://www.test-well.com/cart?add=estradiol&utm_source=ai_agent&utm_medium=markdown
2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA.
3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email.
4. Walk into any Quest Diagnostics, Labcorp, BioReference (NY & NJ) patient service center — no appointment needed at most sites.
5. Results post to your TestWell portal in 1–3 business days with reference ranges and flags.

## Related

- [Blood Tests for Women's Health](https://www.test-well.com/guides/blood-tests-for-womens-health)
- [Women's Fertility Essentials](https://www.test-well.com/tests/female-fertility-panel) — 5 tests · $119.99
- [Erectile Dysfunction Panel](https://www.test-well.com/tests/erectile-dysfunction-panel) — 7 tests · $114.99
- [Men's Hormone Panel](https://www.test-well.com/tests/mens-hormone-panel) — 7 tests · $199.99
- [Prolactin](https://www.test-well.com/tests/prolactin) — $39.99
- [All Fertility tests](https://www.test-well.com/tests/category/fertility)
- [Full test directory](https://www.test-well.com/tests/directory)

---

Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md

Canonical page: https://www.test-well.com/tests/estradiol
Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt

Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.
