---
title: CA-125 (Ovarian Cancer Marker) Test
type: test
id: ca-125
url: "https://www.test-well.com/tests/ca-125-test"
price_usd: 34.99
lab_fee_usd: 6
all_in_usd: 40.99
cpt: 86304
category: Cancer Screening
sample: Blood draw
fasting_required: false
results_in: "2–4 business days"
labs:
  - Labcorp
orderable: true
reviewed_at: 2026-09-14
order_url: "https://www.test-well.com/cart?add=ca-125-test&utm_source=ai_agent&utm_medium=markdown"
---

# CA-125 (Ovarian Cancer Marker) Test

> A tumor marker used to monitor ovarian cancer treatment and screen high-risk women, measured from a standard blood draw. At TestWell it costs $34.99 plus a $6 lab fee, needs no fasting, and results post in 2–4 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Labcorp.

## Key facts

| Fact | Value |
| --- | --- |
| Price | $34.99 + $6 lab processing fee per order ($40.99 all-in for this test alone) |
| CPT code | 86304 |
| Sample | Blood draw |
| Fasting | Not required |
| Results | 2–4 business days |
| Labs | Labcorp |
| Biomarkers measured | 1 |
| Physician authorization | Included — no doctor's visit, referral or insurance needed |
| Payment | Card, HSA or FSA; cash-pay only (no insurance billing) |

## What does the CA-125 (Ovarian Cancer Marker) test tell you?

A tumor marker used to monitor ovarian cancer treatment and screen high-risk women.

CA-125 is a protein found on the surface of ovarian cancer cells and some normal tissues. Elevated levels can indicate ovarian cancer, especially in postmenopausal women. It is primarily used to monitor treatment response and recurrence rather than initial screening in the general population. CA-125 can also be elevated in endometriosis, pelvic inflammatory disease, liver disease, and during menstruation or pregnancy.

**Clinical use:** Cancer Antigen 125 — a protein elevated in ~80% of ovarian cancers. Used for monitoring known ovarian cancer treatment response and surveillance, NOT recommended as a general screening test in average-risk women.

## Who should order it?

Women already diagnosed with ovarian cancer (monitoring treatment + recurrence), BRCA1/2 mutation carriers (selective screening), women with persistent pelvic mass on imaging to help stratify malignancy risk. NOT recommended for asymptomatic average-risk screening.

## Biomarkers measured

- [CA-125](https://www.test-well.com/biomarkers/ca-125)

## Price by lab

| Lab | Test price | All-in (with $6 fee) | Notes |
| --- | --- | --- | --- |
| Labcorp | $34.99 | $40.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) |

Rhode Island is not served. Prices are identical online and in the lab; no draw fee or physician fee is added.

## How much does a CA-125 (Ovarian Cancer Marker) test cost?

A CA-125 (Ovarian Cancer Marker) test costs $34.99 at TestWell — $40.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Hospital outpatient labs typically bill around $200.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.

| Where you order | Price | One test, all-in | Notes |
| --- | --- | --- | --- |
| TestWell (drawn at Quest or Labcorp) | $34.99 | $40.99 | Includes the one $6 lab processing fee, charged once per order |
| Hospital outpatient lab, self-pay (typical) | $200.00 | $200.00 | Reference figure; hospital charges vary widely by facility and are often higher |

Lab test codes: Quest test code 29256 · Labcorp test no. 002303.

## How do you prepare?

No fasting required.

## Related conditions

- Ovarian cancer (C56.9)
- Endometriosis (N80.9)
- Pelvic inflammatory disease (N73.9)
- Uterine fibroids (D25.9)


## Common questions about the CA-125 (Ovarian Cancer Marker) test

### Should I get CA-125 as a screening test?

No, unless you have a known BRCA1/2 mutation or other high-risk genetic syndrome. CA-125 has a high false-positive rate in average-risk women (elevated by endometriosis, fibroids, pregnancy, inflammation) and randomized trials show no mortality benefit from screening average-risk women. USPSTF specifically recommends against it.

### What's a normal CA-125 level?

Most labs use under 35 U/mL as normal. But 1-2% of healthy women have elevated CA-125 without cancer. Trends over time matter more than single values — a stable mildly-elevated CA-125 is rarely concerning; a rapidly rising CA-125 in someone with prior ovarian cancer is a red flag for recurrence.

### When is CA-125 most useful?

(1) Monitoring response to chemotherapy in known ovarian cancer (numbers should fall during effective treatment). (2) Surveillance for recurrence after initial cancer treatment. (3) Combined with transvaginal ultrasound to estimate malignancy risk in a woman with a known pelvic mass (the ROMA score).

### How much does a CA-125 test cost without insurance?

On TestWell, CA-125 is $34.99. Quest Direct lists the same test at $45, walk-in hospital labs typically bill $150-200 without insurance.

### What is the CPT code for CA-125?

The CPT code for CA-125 is 86304.

### Do I need to fast?

No fasting required. Avoid testing during your menstrual period — menstruation can transiently elevate CA-125 and produce a false-positive.

### What can cause a false-positive CA-125?

Endometriosis, uterine fibroids, pelvic inflammatory disease, pregnancy (first trimester), liver disease, recent abdominal surgery, and even ovulation can transiently elevate CA-125. This is why it's not a good screening test in average-risk women — the false-positive rate is too high.

## How to order

1. Add to cart: https://www.test-well.com/cart?add=ca-125-test&utm_source=ai_agent&utm_medium=markdown
2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA.
3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email.
4. Walk into any Labcorp patient service center — no appointment needed at most sites.
5. Results post to your TestWell portal in 2–4 business days with reference ranges and flags.

## Related

- [Women's Cancer Screening Panel](https://www.test-well.com/tests/womens-cancer-screening-panel) — 12 tests · $299.99
- [CA 19-9 (Pancreatic Cancer Marker)](https://www.test-well.com/tests/ca-19-9-test) — $28.99
- [Colon Cancer Screening Test (FIT)](https://www.test-well.com/tests/fit-fecal-immunochemical-test) — $59.99
- [Galleri Multi-Cancer Early Detection Test](https://www.test-well.com/tests/galleri-multi-cancer-detection) — $949.99
- [All Cancer Screening tests](https://www.test-well.com/tests/category/cancer-screening)
- [Full test directory](https://www.test-well.com/tests/directory)

---

Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md

Canonical page: https://www.test-well.com/tests/ca-125-test
Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt

Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.
