---
title: Autoimmune Screening Panel
type: panel
id: autoimmune-screening-panel
url: "https://www.test-well.com/tests/autoimmune-screening-panel"
price_usd: 86.99
lab_fee_usd: 6
all_in_usd: 92.99
tests_included: 4
biomarkers_measured: 6
category: Inflammation & Autoimmune
sample: Blood draw
fasting_required: false
results_in: "3–5 business days"
labs:
  - Quest
  - Labcorp
  - BioReference
orderable: true
order_url: "https://www.test-well.com/cart?add=autoimmune-screening-panel&utm_source=ai_agent&utm_medium=markdown"
---

# Autoimmune Screening Panel

> Autoimmune Screening Panel bundles 4 tests — Autoimmune Antibody Screen (ANA), Heart & Body Inflammation Test (hs-CRP) and Body Inflammation Test (ESR) plus 1 more — for $86.99 all-in (about $21.75 per test). No fasting is needed; results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp.

*ANA with reflex, rheumatoid factor and both inflammation markers — the first-line autoimmune work-up*

## Key facts

| Fact | Value |
| --- | --- |
| Price | $86.99 + $6 lab processing fee per order ($92.99 all-in) |
| Versus buying separately | $108.96 for the 4 tests individually — the panel saves 20% |
| Tests included | 4 |
| Biomarkers measured | 6 |
| Sample | Blood draw |
| Fasting | Not required |
| Results | 3–5 business days |
| Labs | Quest Diagnostics, Labcorp, BioReference (NY & NJ) |
| Physician authorization | Included — no doctor's visit, referral or insurance needed |

## What does the Autoimmune Screening Panel cover?

ANA screen with reflex to the specific-antibody panel, rheumatoid factor, ESR and hs-CRP: the blood tests clinicians order first when joint pain, rashes, fatigue or dry eyes raise the question of an autoimmune disease.

When symptoms suggest an autoimmune condition — joint pain and swelling, a photosensitive rash, unexplained fevers or fatigue, dry eyes and mouth, Raynaud's colour changes — the first blood tests answer two questions: is there systemic inflammation, and are there autoantibodies? This panel measures ESR and high-sensitivity CRP for inflammation, rheumatoid factor for rheumatoid arthritis, and an ANA screen that automatically reflexes to titer, pattern and the specific-antibody panel (anti-dsDNA, Smith, SSA/SSB, RNP, Scl-70, centromere, Jo-1) when positive — so a positive screen leaves with the antibodies that point toward lupus, Sjögren's or scleroderma instead of a second visit. Read the results together: a positive ANA alone is common in healthy people, while positive specific antibodies with raised inflammation markers and symptoms warrant a rheumatology referral. No fasting is needed.

## Who should order it?

Adults with persistent joint pain or swelling, unexplained rashes or fevers, dry eyes and mouth, Raynaud's, or a family history of lupus, rheumatoid arthritis or Sjögren's who want the first-line work-up before a specialist visit.

## Tests included

| Test | Biomarkers | Standalone price | CPT |
| --- | --- | --- | --- |
| [Autoimmune Antibody Screen (ANA)](https://www.test-well.com/tests/ana-screen) | 3 (ANA Screen, Titer (if positive), Pattern (if positive)) | $32.99 | 86038 |
| [Heart & Body Inflammation Test (hs-CRP)](https://www.test-well.com/tests/hs-crp) | 1 (hs-CRP) | $34.99 | 86141 |
| [Body Inflammation Test (ESR)](https://www.test-well.com/tests/sed-rate) | 1 (ESR) | $18.99 | 85652 |
| [Rheumatoid Factor (RF)](https://www.test-well.com/tests/rheumatoid-factor) | 1 (Rheumatoid Factor) | $21.99 | 86431 |

## Price by lab

| Lab | Panel price | All-in (with $6 fee) | Notes |
| --- | --- | --- | --- |
| Quest Diagnostics | $86.99 | $92.99 | Choose at checkout |
| Labcorp | $86.99 | $92.99 | Choose at checkout |
| BioReference (NY & NJ) | $86.99 | $92.99 | New York and New Jersey orders route here automatically |

## How much does a Autoimmune Screening Panel cost?

A Autoimmune Screening Panel costs $86.99 at TestWell — $92.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible.

| Where you order | Price | One test, all-in | Notes |
| --- | --- | --- | --- |
| TestWell (drawn at Quest or Labcorp) | $86.99 | $92.99 | Includes the one $6 lab processing fee, charged once per order |

## How do you prepare?

No fasting required. Avoid vigorous exercise for 24 hours before the draw (it can raise CRP). Tell your clinician about medications — several can cause a positive ANA.


## Common questions about the Autoimmune Screening Panel

### What blood tests screen for autoimmune disease?

The first-line set is an ANA (antinuclear antibody) screen for the connective-tissue diseases such as lupus, Sjögren's and scleroderma; rheumatoid factor (often with anti-CCP) for rheumatoid arthritis; and the two inflammation markers, ESR and CRP. Depending on symptoms clinicians add anti-CCP, HLA-B27 for spondyloarthritis, celiac antibodies, thyroid antibodies or ANCA. No panel screens for every autoimmune disease — this one covers the conditions behind most joint, skin and fatigue presentations.

### What does a positive ANA with normal inflammation markers mean?

Usually less than it sounds. Up to one in five healthy adults has a low-titer positive ANA, and without symptoms or elevated ESR/CRP it is typically monitored rather than treated. The reflexed specific-antibody panel is what adds weight: anti-dsDNA or anti-Smith point strongly to lupus, SSA/SSB to Sjögren's, centromere or Scl-70 to scleroderma. Bring the titer, pattern and specific antibodies to a clinician rather than acting on the screen alone.

## How to order

1. Add to cart: https://www.test-well.com/cart?add=autoimmune-screening-panel&utm_source=ai_agent&utm_medium=markdown
2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA.
3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email.
4. One draw at any Quest Diagnostics, Labcorp, BioReference (NY & NJ) patient service center covers every test in the panel.
5. Results post to your TestWell portal in 3–5 business days.

## Related

- [Autoimmune Advanced Panel](https://www.test-well.com/tests/autoimmune-advanced-panel) — 11 tests · $159.99
- [Autoimmune Panel](https://www.test-well.com/tests/autoimmune-panel) — 5 tests · $129.99
- [Inflammation Panel](https://www.test-well.com/tests/inflammation-panel) — 7 tests · $119.99
- [All Inflammation & Autoimmune tests](https://www.test-well.com/tests/category/inflammation-autoimmune)
- [Full test directory](https://www.test-well.com/tests/directory)

---

Canonical page: https://www.test-well.com/tests/autoimmune-screening-panel
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Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.