--- title: Autoimmune Panel type: panel id: autoimmune-panel url: "https://www.test-well.com/tests/autoimmune-panel" price_usd: 129.99 lab_fee_usd: 6 all_in_usd: 135.99 tests_included: 5 biomarkers_measured: 7 category: Inflammation & Autoimmune sample: Blood draw fasting_required: false results_in: "3–5 business days" labs: - Quest - Labcorp orderable: true reviewed_at: 2026-09-14 order_url: "https://www.test-well.com/cart?add=autoimmune-panel&utm_source=ai_agent&utm_medium=markdown" --- # Autoimmune Panel > Autoimmune Panel bundles 5 tests — Autoimmune Antibody Screen (ANA), Rheumatoid Factor (RF) and Rheumatoid Arthritis Antibody Test (Anti-CCP) plus 2 more — for $129.99 all-in (about $26.00 per test). No fasting is needed; results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; one draw at Quest or Labcorp. *Screen for the most common autoimmune conditions* ## Key facts | Fact | Value | | --- | --- | | Price | $129.99 + $6 lab processing fee per order ($135.99 all-in) | | Versus buying separately | $141.95 for the 5 tests individually — the panel saves 8% | | Tests included | 5 | | Biomarkers measured | 7 | | Sample | Blood draw | | Fasting | Not required | | Results | 3–5 business days | | Labs | Quest Diagnostics, Labcorp | | Physician authorization | Included — no doctor's visit, referral or insurance needed | ## What does the Autoimmune Panel cover? Screens for lupus, rheumatoid arthritis, and systemic inflammation with ANA, RF, Anti-CCP, hs-CRP, and Sed Rate. The Autoimmune Panel combines five key markers to screen for the most common autoimmune conditions. ANA detects antibodies associated with lupus and other connective tissue diseases. Rheumatoid Factor and Anti-CCP target rheumatoid arthritis from two angles — RF for sensitivity and Anti-CCP for specificity. hs-CRP and Sed Rate measure systemic inflammation, which is elevated in most active autoimmune conditions. This panel is ideal for anyone experiencing joint pain, fatigue, rashes, or other unexplained symptoms. **Clinical use:** First-line autoimmune workup: ANA Screen, Rheumatoid Factor, Anti-CCP, hs-CRP, ESR. Screens for the major autoimmune disease categories (lupus, RA, Sjögren's, scleroderma) plus inflammation markers. ## Who should order it? Anyone with joint pain + swelling lasting >6 weeks, unexplained rashes, recurrent low-grade fevers, family history of autoimmune disease, or multi-system symptoms (fatigue + joint pain + skin changes). ## Tests included | Test | Biomarkers | Standalone price | CPT | | --- | --- | --- | --- | | [Autoimmune Antibody Screen (ANA)](https://www.test-well.com/tests/ana-screen) | 3 (ANA Screen, Titer (if positive), Pattern (if positive)) | $32.99 | 86038 | | [Rheumatoid Factor (RF)](https://www.test-well.com/tests/rheumatoid-factor) | 1 (Rheumatoid Factor) | $21.99 | 86431 | | [Rheumatoid Arthritis Antibody Test (Anti-CCP)](https://www.test-well.com/tests/anti-ccp-antibody) | 1 (Anti-CCP Antibodies) | $32.99 | 86200 | | [Heart & Body Inflammation Test (hs-CRP)](https://www.test-well.com/tests/hs-crp) | 1 (hs-CRP) | $34.99 | 86141 | | [Body Inflammation Test (ESR)](https://www.test-well.com/tests/sed-rate) | 1 (ESR) | $18.99 | 85652 | ## Price by lab | Lab | Panel price | All-in (with $6 fee) | Notes | | --- | --- | --- | --- | | Quest Diagnostics | $129.99 | $135.99 | Choose at checkout | | Labcorp | $129.99 | $135.99 | Choose at checkout | ## How much does a Autoimmune Panel cost? A Autoimmune Panel costs $129.99 at TestWell — $135.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. | Where you order | Price | One test, all-in | Notes | | --- | --- | --- | --- | | TestWell (drawn at Quest or Labcorp) | $129.99 | $135.99 | Includes the one $6 lab processing fee, charged once per order | ## How do you prepare? No fasting required. Inform your provider if you are taking immunosuppressive medications. ## Related conditions - Systemic lupus erythematosus (M32.9) - Rheumatoid arthritis (M06.9) - Sjögren syndrome (M35.00) - Mixed connective tissue disease (M35.1) ## Common questions about the Autoimmune Panel ### What's included in the Autoimmune Panel? [ANA Screen](https://www.test-well.com/tests/ana-screen) (lupus + connective tissue diseases), [Rheumatoid Factor](https://www.test-well.com/tests/rheumatoid-factor) (RA), [Anti-CCP](https://www.test-well.com/tests/anti-ccp-antibody) (RA specifically — more sensitive than RF), [hs-CRP](https://www.test-well.com/tests/hs-crp) (inflammation), and ESR / [sed rate](https://www.test-well.com/tests/sed-rate) (inflammation). Together they cover the major autoimmune disease categories. ### What does a positive ANA mean? [ANA](https://www.test-well.com/tests/ana-screen) positive (above 1:80 titer) is found in ~15% of healthy adults — most have no autoimmune disease. High titers (>1:320) combined with symptoms or other positive markers (anti-dsDNA, anti-Smith) point to lupus or related conditions. The pattern (homogeneous, speckled, etc.) helps narrow the diagnosis. ### How is this different from the Autoimmune Advanced Panel? Standard Autoimmune Panel: 5 first-line tests for general screening. [Autoimmune Advanced Panel](https://www.test-well.com/tests/autoimmune-advanced-panel) at $159 adds disease-specific antibodies (anti-dsDNA, anti-Smith, ANCA, anti-Ro/La, complement levels) — useful when ANA is positive and you need to nail down the specific disease. ### How much does the Autoimmune Panel cost without insurance? On TestWell, the Autoimmune Panel is $129.99. Ordering the same 5 tests separately would be about $170. Quest Direct lists comparable bundles at $175, walk-in hospital labs typically bill $400-600 for the same biomarkers without insurance. ### Do I need to fast? No fasting required. Avoid intense exercise for 24 hours before draw, since both [hs-CRP](https://www.test-well.com/tests/hs-crp) and ESR can be transiently elevated by muscle inflammation. ### What if all tests are normal but I still have symptoms? Many autoimmune diseases (early lupus, axial spondyloarthritis, fibromyalgia) can have normal screening labs. Persistent symptoms warrant rheumatology referral regardless of lab results — clinical exam + imaging + symptom pattern matter as much as labs. ### How often should I retest? Once for screening if symptoms are unexplained. Repeat positive findings every 6-12 months to track disease activity. Inflammation markers ([hs-CRP](https://www.test-well.com/tests/hs-crp), ESR) can be retested every 3-6 months to monitor treatment response in known autoimmune disease. ## How to order 1. Add to cart: https://www.test-well.com/cart?add=autoimmune-panel&utm_source=ai_agent&utm_medium=markdown 2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA. 3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email. 4. One draw at any Quest Diagnostics, Labcorp patient service center covers every test in the panel. 5. Results post to your TestWell portal in 3–5 business days. ## Related - [ANA Test Results Explained: Titers, Patterns, and What a Positive ANA Means](https://www.test-well.com/guides/ana-test-results-explained) - [Autoimmune Advanced Panel](https://www.test-well.com/tests/autoimmune-advanced-panel) — 11 tests · $159.99 - [Autoimmune Screening Panel](https://www.test-well.com/tests/autoimmune-screening-panel) — 4 tests · $86.99 - [Inflammation Panel](https://www.test-well.com/tests/inflammation-panel) — 7 tests · $119.99 - [All Inflammation & Autoimmune tests](https://www.test-well.com/tests/category/inflammation-autoimmune) - [Full test directory](https://www.test-well.com/tests/directory) --- Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md Canonical page: https://www.test-well.com/tests/autoimmune-panel Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.