--- title: Autoimmune Antibody Screen (ANA) Test type: test id: ana url: "https://www.test-well.com/tests/ana-screen" price_usd: 32.99 lab_fee_usd: 6 all_in_usd: 38.99 cpt: 86038 category: Inflammation & Autoimmune sample: Blood draw fasting_required: false results_in: "3–5 business days" labs: - Quest - Labcorp - BioReference orderable: true reviewed_at: 2026-09-14 order_url: "https://www.test-well.com/cart?add=ana-screen&utm_source=ai_agent&utm_medium=markdown" --- # Autoimmune Antibody Screen (ANA) Test > Autoimmune Antibody Screen (ANA) measures ANA Screen, Titer (if positive) and Pattern (if positive) from a standard blood draw. At TestWell it costs $32.99 plus a $6 lab fee, needs no fasting, and results post in 3–5 business days. Physician-authorized with no doctor's visit or insurance needed; draw at Quest or Labcorp. ## Key facts | Fact | Value | | --- | --- | | Price | $32.99 + $6 lab processing fee per order ($38.99 all-in for this test alone) | | CPT code | 86038 | | Sample | Blood draw | | Fasting | Not required | | Results | 3–5 business days | | Labs | Quest Diagnostics, Labcorp, BioReference (NY & NJ) | | Biomarkers measured | 3 | | Physician authorization | Included — no doctor's visit, referral or insurance needed | | Payment | Card, HSA or FSA; cash-pay only (no insurance billing) | ## What does the Autoimmune Antibody Screen (ANA) test tell you? Screens for autoimmune conditions like lupus, Sjögren's, and scleroderma. The Antinuclear Antibody (ANA) Screen uses immunofluorescence to detect antibodies that attack your own cell nuclei. A positive ANA can indicate autoimmune conditions including lupus (SLE), Sjögren's syndrome, scleroderma, rheumatoid arthritis, and mixed connective tissue disease. If positive, the reflex titer and pattern help narrow down the specific condition. **Clinical use:** Antinuclear Antibody screen — the gateway test for systemic autoimmune disease. Positive in 95%+ of lupus, 60-80% of Sjögren's, and most autoimmune connective-tissue disorders. ## Who should order it? Anyone with unexplained joint pain, rashes, fatigue, dry eyes/mouth, hair loss, or family history of autoimmune disease. The single best screening test before pursuing specific autoimmune workups. ## Biomarkers measured - ANA Screen - Titer (if positive) - Pattern (if positive) ## Price by lab | Lab | Test price | All-in (with $6 fee) | Notes | | --- | --- | --- | --- | | Quest Diagnostics | $32.99 | $38.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) | | Labcorp | $32.99 | $38.99 | Choose at checkout; walk-in patient service centers nationwide (not NY/NJ) | | BioReference (NY & NJ) | $23.99 | $29.99 | New York and New Jersey orders route here automatically | Rhode Island is not served. Prices are identical online and in the lab; no draw fee or physician fee is added. ## How much does a Autoimmune Antibody Screen (ANA) test cost? A Autoimmune Antibody Screen (ANA) test costs $32.99 at TestWell — $38.99 all-in when ordered alone, because the $6 lab processing fee is charged once per order, with no draw fee or physician fee added. Ordered directly from the labs' own consumer sites, the closest equivalent lists at $112.00 at Quest Health (list prices checked Sep 12, 2026; see the notes on how the products differ). Hospital outpatient labs typically bill around $180.00 self-pay for the same test, and often more. With insurance, what you pay depends on your deductible and your plan's negotiated rate; TestWell's price is fixed before the draw and is HSA/FSA-eligible. | Where you order | Price | One test, all-in | Notes | | --- | --- | --- | --- | | TestWell (drawn at Quest or Labcorp) | $32.99 | $38.99 | Includes the one $6 lab processing fee, charged once per order | | Quest Health (Quest Diagnostics' own site) | $112.00 | $112.00 | Both reflex to an antibody panel on a positive ANA · [list price checked 2026-09-12](https://www.questhealth.com/product/autoimmune-screening-test-ana-with-reflex/16814M.html) | | Hospital outpatient lab, self-pay (typical) | $180.00 | $180.00 | Reference figure; hospital charges vary widely by facility and are often higher | Lab test codes: Quest test code 16814 · Labcorp test no. 164855 · BioReference code 0038-0. ## How do you prepare? No fasting required. No special preparation needed. ## Related conditions - Systemic lupus erythematosus (M32.9) - Sjögren's syndrome (M35.00) - Mixed connective tissue disease (M35.1) - [Autoimmune disease screening](https://www.test-well.com/conditions/autoimmune-screening) (M35.9) ## Common questions about the Autoimmune Antibody Screen (ANA) test ### What does a positive ANA mean? A positive ANA alone doesn't diagnose any specific condition. About 5-15% of healthy people have a low-titer positive ANA. Higher titers (1:320+) and specific patterns (homogeneous, speckled, nucleolar) point toward specific diseases — but a clinician needs to interpret in context with symptoms and follow-up specific antibody tests. ### How much does an ANA test cost without insurance? TestWell charges $32.99 — vs $49 at Quest Direct and $80-$200 at hospital labs. ### Do I need to fast? No fasting required. ### What's the difference between ANA Screen and ANA with Reflex? ANA Screen reports positive/negative + titer + pattern. ANA with Reflex automatically runs specific antibody tests (anti-dsDNA, anti-Smith, anti-RNP, anti-SSA/SSB) if the screen is positive — saves a follow-up draw. We default to ANA with reflex for symptomatic patients. ### What's the CPT code? 86038 (ANA). HSA/FSA eligible. ### How often should I retest? Once positive, titer can change with disease activity. Retest every 3-6 months if monitoring an established autoimmune diagnosis; annually if positive but asymptomatic. ## How to order 1. Add to cart: https://www.test-well.com/cart?add=ana-screen&utm_source=ai_agent&utm_medium=markdown 2. Create an account or sign in, confirm your state and preferred lab, pay by card, HSA or FSA. 3. A licensed physician authorizes the order (usually within minutes); the requisition arrives by email. 4. Walk into any Quest Diagnostics, Labcorp, BioReference (NY & NJ) patient service center — no appointment needed at most sites. 5. Results post to your TestWell portal in 3–5 business days with reference ranges and flags. ## Related - [ANA Test Results Explained: Titers, Patterns, and What a Positive ANA Means](https://www.test-well.com/guides/ana-test-results-explained) - [Autoimmune Screening Panel](https://www.test-well.com/tests/autoimmune-screening-panel) — 4 tests · $86.99 - [Autoimmune Panel](https://www.test-well.com/tests/autoimmune-panel) — 5 tests · $129.99 - [Autoimmune Advanced Panel](https://www.test-well.com/tests/autoimmune-advanced-panel) — 11 tests · $159.99 - [Rheumatoid Arthritis Antibody Test (Anti-CCP)](https://www.test-well.com/tests/anti-ccp-antibody) — $32.99 - [Sed Rate (ESR)](https://www.test-well.com/tests/sed-rate-esr) — $24.99 - [All Inflammation & Autoimmune tests](https://www.test-well.com/tests/category/inflammation-autoimmune) - [Full test directory](https://www.test-well.com/tests/directory) --- Medically reviewed by Youmna DiStefano, MD (Medical Reviewer, TestWell); last reviewed 2026-09-14. Review policy: https://www.test-well.com/reviewers/youmna-distefano-md Canonical page: https://www.test-well.com/tests/ana-screen Machine-readable catalog: https://www.test-well.com/api/catalog.json · MCP server: https://www.test-well.com/mcp · Overview for agents: https://www.test-well.com/llms.txt Prices are cash-pay, in USD, and include physician authorization; every order adds one flat $6 lab processing fee. Educational content is not a diagnosis — discuss results with a clinician.